Is the New Variant RHDV Replacing Genogroup 1 in Portuguese Wild Rabbit Populations?
AbstractThe Lagovirus rabbit hemorrhagic disease virus (RHDV), a member of the family Caliciviridae, severely affects European rabbit (Oryctolagus cuniculus) populations by causing rabbit hemorrhagic disease (RHD). RHDV is subdivided in six genogroups but, more recently, a new RHDV variant with a unique genetic and antigenic profile emerged. We performed a study in rabbits found dead in the field during 2013 and 2014 in Portugal to determine the prevalence of this new variant versus the classical RHDV. Fifty-seven liver samples were screened for the presence of RHDV and positive samples were genotyped. All cases of RHDV infection were caused by the new variant. The only former genogroup circulating in Portugal, G1, was not detected. We hence conclude that the new RHDV variant is replacing G1 in Portugal, probably due to a selective advantage. This sudden and rapid replacement emphasizes the necessity of continued monitoring of wild rabbit populations. View Full-Text
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Lopes, A.M.; Correia, J.; Abrantes, J.; Melo, P.; Ramada, M.; Magalhães, M.J.; Alves, P.C.; Esteves, P.J. Is the New Variant RHDV Replacing Genogroup 1 in Portuguese Wild Rabbit Populations? Viruses 2015, 7, 27-36.
Lopes AM, Correia J, Abrantes J, Melo P, Ramada M, Magalhães MJ, Alves PC, Esteves PJ. Is the New Variant RHDV Replacing Genogroup 1 in Portuguese Wild Rabbit Populations? Viruses. 2015; 7(1):27-36.Chicago/Turabian Style
Lopes, Ana M.; Correia, Jorge; Abrantes, Joana; Melo, Pedro; Ramada, Margarida; Magalhães, Maria J.; Alves, Paulo C.; Esteves, Pedro J. 2015. "Is the New Variant RHDV Replacing Genogroup 1 in Portuguese Wild Rabbit Populations?" Viruses 7, no. 1: 27-36.