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Editorial

Paving the Way to Unveil the Diversity and Evolution of Phage Genomes

by 1,2,* and 3,*
1
Max Planck Tandem Group in Computational Biology, Department of Biological Sciences, School of Sciences, Universidad de los Andes, Bogotá 111711, Colombia
2
Department of Pathology and Immunology, The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St Louis, MO 63108, USA
3
Department of Biological Sciences, School of Sciences, Universidad de los Andes, Bogotá 111711, Colombia
*
Authors to whom correspondence should be addressed.
Viruses 2020, 12(9), 905; https://doi.org/10.3390/v12090905
Received: 12 August 2020 / Accepted: 13 August 2020 / Published: 19 August 2020
(This article belongs to the Special Issue Diversity and Evolution of Phage Genomes)
Phage biology has been developing for the last hundred years, and the potential of phages as tools and treatments has been known since their early discovery. However, the lack of knowledge of the molecular mechanisms coded in phage genomes hindered the development of the field. With current molecular methods, the last decade has been a resurgence of the field. The Special Issue on “Diversity and Evolution of Phage Genomes” is a great example with its 17 manuscripts published. It covers some of the latest methods to sample and characterize environmental and host associated viromes, considering experimental biases and computational developments. Furthermore, the use of molecular tools coupled with traditional methods has allowed to isolate and characterize viruses from different hosts and environments with such diversity that even a new viral class is being proposed. The viruses described cover all different phage families and lifestyles. However, is not only about diversity; the molecular evolution is studied in a set of manuscripts looking at phage-host interactions and their capacity to uncover the frequency and type of mutations behind the bacterial resistance mechanisms and viral pathogenesis, and such methods are opening new ways into identifying potential receptors and characterizing the bacterial host range. View Full-Text
Keywords: viral diversity; viral evolution; next generation sequencing; viromes; molecular methods viral diversity; viral evolution; next generation sequencing; viromes; molecular methods
MDPI and ACS Style

Reyes, A.; Vives, M.J. Paving the Way to Unveil the Diversity and Evolution of Phage Genomes. Viruses 2020, 12, 905. https://doi.org/10.3390/v12090905

AMA Style

Reyes A, Vives MJ. Paving the Way to Unveil the Diversity and Evolution of Phage Genomes. Viruses. 2020; 12(9):905. https://doi.org/10.3390/v12090905

Chicago/Turabian Style

Reyes, Alejandro, and Martha J. Vives. 2020. "Paving the Way to Unveil the Diversity and Evolution of Phage Genomes" Viruses 12, no. 9: 905. https://doi.org/10.3390/v12090905

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