Next Article in Journal
Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors
Previous Article in Journal
Coxsackievirus B3 Infection of Human Neural Progenitor Cells Results in Distinct Expression Patterns of Innate Immune Genes
Open AccessCommunication

Metagenomic Detection of Two Vientoviruses in a Human Sputum Sample

1
Servicio de Microbiología, Hospital Universitario La Paz, Idipaz, 28046 Madrid, Spain
2
Cancer Epigenetics Laboratory, Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz, 28046 Madrid, Spain
3
Sección de Infecciosas and Unidad de Medicina Tropical y del Viajero, Servicio de Medicina Interna, Hospital Universitario La Paz, 28046 Madrid, Spain
4
Unidad de Medicina Intensiva, Hospital Universitario La Paz, 28046 Madrid, Spain
5
CBRN & Infectious Diseases Unit, Hospital Central de la Defensa Gómez Ulla, 28047 Madrid, Spain
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Viruses 2020, 12(3), 327; https://doi.org/10.3390/v12030327
Received: 21 January 2020 / Revised: 6 March 2020 / Accepted: 17 March 2020 / Published: 18 March 2020
(This article belongs to the Section Animal Viruses)
We used metagenomics to analyze one sputum sample from a patient with symptoms of a respiratory infection that yielded negative results for all pathogens tested. We detected two viral genomes that could be assembled and showed sequence similarity to redondoviruses, a recently described group within the CRESS-DNA viruses. One hundred sputum samples were screened for the presence of these viruses using specific primers. One sample was positive for the same two viruses, and another was positive for one of them. These findings raise questions about a possible role of redondoviruses in respiratory infections in humans. View Full-Text
Keywords: circoviruses; redondoviruses; metagenomics; respiratory disease circoviruses; redondoviruses; metagenomics; respiratory disease
Show Figures

Figure 1

MDPI and ACS Style

Lázaro-Perona, F.; Dahdouh, E.; Román-Soto, S.; Jiménez-Rodríguez, S.; Rodríguez-Antolín, C.; de la Calle, F.; Agrifoglio, A.; Membrillo, F.J.; García-Rodríguez, J.; Mingorance, J. Metagenomic Detection of Two Vientoviruses in a Human Sputum Sample. Viruses 2020, 12, 327. https://doi.org/10.3390/v12030327

AMA Style

Lázaro-Perona F, Dahdouh E, Román-Soto S, Jiménez-Rodríguez S, Rodríguez-Antolín C, de la Calle F, Agrifoglio A, Membrillo FJ, García-Rodríguez J, Mingorance J. Metagenomic Detection of Two Vientoviruses in a Human Sputum Sample. Viruses. 2020; 12(3):327. https://doi.org/10.3390/v12030327

Chicago/Turabian Style

Lázaro-Perona, Fernando; Dahdouh, Elias; Román-Soto, Sergio; Jiménez-Rodríguez, Sonia; Rodríguez-Antolín, Carlos; de la Calle, Fernando; Agrifoglio, Alexander; Membrillo, Francisco J.; García-Rodríguez, Julio; Mingorance, Jesús. 2020. "Metagenomic Detection of Two Vientoviruses in a Human Sputum Sample" Viruses 12, no. 3: 327. https://doi.org/10.3390/v12030327

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop