Cell Culture Models for Hepatitis E Virus
AbstractDespite a growing awareness, hepatitis E virus (HEV) remains understudied and investigations have been historically hampered by the absence of efficient cell culture systems. As a result, the pathogenesis of HEV infection and basic steps of the HEV life cycle are poorly understood. Major efforts have recently been made through the development of HEV infectious clones and cellular systems that significantly advanced HEV research. Here, we summarize these systems, discussing their advantages and disadvantages for HEV studies. We further capitalize on the need for HEV-permissive polarized cell models to better recapitulate the entire HEV life cycle and transmission. View Full-Text
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Fu, R.M.; Decker, C.C.; Dao Thi, V.L. Cell Culture Models for Hepatitis E Virus. Viruses 2019, 11, 608.
Fu RM, Decker CC, Dao Thi VL. Cell Culture Models for Hepatitis E Virus. Viruses. 2019; 11(7):608.Chicago/Turabian Style
Fu, Rebecca M.; Decker, Charlotte C.; Dao Thi, Viet L. 2019. "Cell Culture Models for Hepatitis E Virus." Viruses 11, no. 7: 608.
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