Next Article in Journal
Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias?
Next Article in Special Issue
Importance of the Host Phenotype on the Preservation of the Genetic Diversity in Codling Moth Granulovirus
Previous Article in Journal
High-Throughput Sequencing Reveals Differential Begomovirus Species Diversity in Non-Cultivated Plants in Northern-Pacific Mexico
Previous Article in Special Issue
Genetic Variability of Chrysodeixis Includens Nucleopolyhedrovirus (ChinNPV) and the Insecticidal Characteristics of Selected Genotypic Variants
Article Menu

Export Article

Open AccessReview

Nucleocapsid Assembly of Baculoviruses

1
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225009, China
2
Joint International Research Laboratory of Agriculture & Agri-Product Safety, Yangzhou University, Yangzhou 225009, China
*
Author to whom correspondence should be addressed.
Viruses 2019, 11(7), 595; https://doi.org/10.3390/v11070595
Received: 29 May 2019 / Revised: 27 June 2019 / Accepted: 30 June 2019 / Published: 1 July 2019
(This article belongs to the Special Issue Insect Viruses and Pest Management)
  |  
PDF [687 KB, uploaded 1 July 2019]
  |  

Abstract

The baculovirus nucleocapsid is formed through a rod-like capsid encapsulating a genomic DNA molecule of 80~180 kbp. The viral capsid is a large oligomer composed of many copies of various protein subunits. The assembly of viral capsids is a complex oligomerization process. The timing of expression of nucleocapsid-related proteins, transport pathways, and their interactions can affect the assembly process of preformed capsids. In addition, the selection of viral DNA and the injection of the viral genome into empty capsids are the critical steps in nucleocapsid assembly. This paper reviews the replication and recombination of baculovirus DNA, expression and transport of capsid proteins, formation of preformed capsids, DNA encapsulation, and nucleocapsid formation. This review will provide a basis for further study of the nucleocapsid assembly mechanism of baculovirus. View Full-Text
Keywords: nucleocapsid assembly; baculovirus; preformed capsid; DNA packaging; capsid proteins nucleocapsid assembly; baculovirus; preformed capsid; DNA packaging; capsid proteins
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Zhao, S.; He, G.; Yang, Y.; Liang, C. Nucleocapsid Assembly of Baculoviruses. Viruses 2019, 11, 595.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top