Next Article in Journal
Inclusion of Antibodies to Cell Culture Media Preserves the Integrity of Genes Encoding RL13 and the Pentameric Complex Components During Fibroblast Passage of Human Cytomegalovirus
Previous Article in Journal
Terminase Large Subunit Provides a New Drug Target for Herpesvirus Treatment
Previous Article in Special Issue
Viruses of Polar Aquatic Environments
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessReview
Viruses 2019, 11(3), 220; https://doi.org/10.3390/v11030220

Ecological and Evolutionary Processes Shaping Viral Genetic Diversity

1,2,*,†, 3,†, 4,‡ and 1,2,‡
1
Department of Fish Ecology and Evolution, Center for Ecology, Evolution and Biogeochemistry, EAWAG, Swiss Federal Institute of Aquatic Science and Technology, 6047 Kastanienbaum, Switzerland
2
Division of Aquatic Ecology, Institute of Ecology and Evolution, University of Bern, 3012 Bern, Switzerland
3
Section of Population Genetics, TUM School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany
4
Limnological Institute University Konstanz, Aquatic Ecology and Evolution, 78464 Konstanz, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
These authors contributed equally to this work.
Received: 24 January 2019 / Revised: 22 February 2019 / Accepted: 27 February 2019 / Published: 5 March 2019
(This article belongs to the Special Issue Viruses of Microbes V: Biodiversity and Future Applications)
  |  
PDF [1974 KB, uploaded 5 March 2019]
  |     |  

Abstract

The contemporary genomic diversity of viruses is a result of the continuous and dynamic interaction of past ecological and evolutionary processes. Thus, genome sequences of viruses can be a valuable source of information about these processes. In this review, we first describe the relevant processes shaping viral genomic variation, with a focus on the role of host–virus coevolution and its potential to give rise to eco-evolutionary feedback loops. We further give a brief overview of available methodology designed to extract information about these processes from genomic data. Short generation times and small genomes make viruses ideal model systems to study the joint effect of complex coevolutionary and eco-evolutionary interactions on genetic evolution. This complexity, together with the diverse array of lifetime and reproductive strategies in viruses ask for extensions of existing inference methods, for example by integrating multiple information sources. Such integration can broaden the applicability of genetic inference methods and thus further improve our understanding of the role viruses play in biological communities. View Full-Text
Keywords: genetic diversity; viral population genetics; host–virus coevolution; eco-evolutionary feedback genetic diversity; viral population genetics; host–virus coevolution; eco-evolutionary feedback
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Retel, C.; Märkle, H.; Becks, L.; Feulner, P.G.D. Ecological and Evolutionary Processes Shaping Viral Genetic Diversity. Viruses 2019, 11, 220.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top