Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System
Abstract
:1. Introduction
2. The Human Phageome
3. Phages Effects on the Bacterial - Mammalian Host Interface
3.1. Phages and Mucosal Tissues
3.2. Phage Transcytosis
4. Cell Perfusion and Access, Interaction with Intracellular Immune Response
5. Phage Innate Immune Response
5.1. Phage Phagocytosis
5.2. Phage Induced Phagocytosis of Bacteria
5.3. Cytokine Response against Phages
5.4. Phage Adaptive Immune Response
Anti-Phage Antibody Production
5.5. In-Silico Modeling of the Immune Response Towards Phages
6. Anti-Inflammatory Phage Properties Affect the Outcome of Phage Therapy
7. Relevance of Phage-Mammalian Host Immune Responses
8. Conclusions and Areas of Future Investigation
Supplementary Materials
Acknowledgments
Conflicts of Interest
References
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Van Belleghem, J.D.; Dąbrowska, K.; Vaneechoutte, M.; Barr, J.J.; Bollyky, P.L. Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System. Viruses 2019, 11, 10. https://doi.org/10.3390/v11010010
Van Belleghem JD, Dąbrowska K, Vaneechoutte M, Barr JJ, Bollyky PL. Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System. Viruses. 2019; 11(1):10. https://doi.org/10.3390/v11010010
Chicago/Turabian StyleVan Belleghem, Jonas D., Krystyna Dąbrowska, Mario Vaneechoutte, Jeremy J. Barr, and Paul L. Bollyky. 2019. "Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System" Viruses 11, no. 1: 10. https://doi.org/10.3390/v11010010
APA StyleVan Belleghem, J. D., Dąbrowska, K., Vaneechoutte, M., Barr, J. J., & Bollyky, P. L. (2019). Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System. Viruses, 11(1), 10. https://doi.org/10.3390/v11010010