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Article

Artificial Intelligence-Driven Diagnostics in Eye Care: A Random Forest Approach for Data Classification and Predictive Modeling

by
Luís F. F. M. Santos
1,2,
Miguel Ángel Sánchez-Tena
1,3,
Cristina Alvarez-Peregrina
3 and
Clara Martinez-Perez
1,*
1
School of Management, Engineering and Aeronautics, ISEC Lisboa, Instituto Superior de Educação e Ciências, Alameda das Linhas de Torres, 179, 1750-142 Lisbon, Portugal
2
AEROG-LAETA-Aeronautics and Astronautics Research Center, Universidade da Beira Interior, 6201-001 Covilhã, Portugal
3
Optometry and Vision Department, Faculty of Optics and Optometry, Complutense University of Madrid, 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
Algorithms 2025, 18(10), 647; https://doi.org/10.3390/a18100647
Submission received: 10 September 2025 / Revised: 3 October 2025 / Accepted: 11 October 2025 / Published: 15 October 2025
(This article belongs to the Special Issue AI-Assisted Medical Diagnostics)

Abstract

Artificial intelligence and machine learning have increasingly transformed optometry, enabling automated classification and predictive modeling of eye conditions. In this study, we introduce Optometry Random Forest, an artificial intelligence-based system for automated classification and forecasting of optometric data. The proposed methodology leverages Random Forest models, trained on academic optometric datasets, to classify key diagnostic categories, including Contactology, Dry Eye, Low Vision, Myopia, Pediatrics, and Refractive Surgery. Additionally, an autoRegressive integrated moving average based forecasting model is incorporated to predict future research trends in optometry until 2030. Comparing the one-shot and epoch-trained Optometry Random Forest, the findings indicate that the epoch-trained model consistently outperforms the one-shot model, achieving superior classification accuracy (97.17%), precision (97.28%), and specificity (100%). Moreover, the comparative analysis with Optometry Bidirectional Encoder Representations from Transformers demonstrates that the Optometry Random Forest excels in classification reliability and predictive analytics, positioning it as a robust artificial intelligence tool for clinical decision-making and resource allocation. This research highlights the potential of Random Forest models in medical artificial intelligence, offering a scalable and interpretable solution for automated diagnosis, predictive analytics, and artificial intelligence-enhanced decision support in optometry. Future work should focus on integrating real-world clinical datasets to further refine classification performance and enhance the potential for artificial intelligence-driven patient care.
Keywords: machine learning; artificial intelligence; assisted diagnosis; data labeling; knowledge engineering machine learning; artificial intelligence; assisted diagnosis; data labeling; knowledge engineering
Graphical Abstract

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MDPI and ACS Style

Santos, L.F.F.M.; Sánchez-Tena, M.Á.; Alvarez-Peregrina, C.; Martinez-Perez, C. Artificial Intelligence-Driven Diagnostics in Eye Care: A Random Forest Approach for Data Classification and Predictive Modeling. Algorithms 2025, 18, 647. https://doi.org/10.3390/a18100647

AMA Style

Santos LFFM, Sánchez-Tena MÁ, Alvarez-Peregrina C, Martinez-Perez C. Artificial Intelligence-Driven Diagnostics in Eye Care: A Random Forest Approach for Data Classification and Predictive Modeling. Algorithms. 2025; 18(10):647. https://doi.org/10.3390/a18100647

Chicago/Turabian Style

Santos, Luís F. F. M., Miguel Ángel Sánchez-Tena, Cristina Alvarez-Peregrina, and Clara Martinez-Perez. 2025. "Artificial Intelligence-Driven Diagnostics in Eye Care: A Random Forest Approach for Data Classification and Predictive Modeling" Algorithms 18, no. 10: 647. https://doi.org/10.3390/a18100647

APA Style

Santos, L. F. F. M., Sánchez-Tena, M. Á., Alvarez-Peregrina, C., & Martinez-Perez, C. (2025). Artificial Intelligence-Driven Diagnostics in Eye Care: A Random Forest Approach for Data Classification and Predictive Modeling. Algorithms, 18(10), 647. https://doi.org/10.3390/a18100647

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