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Open AccessArticle

Revisiting Chameleon Sequences in the Protein Data Bank

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
Algorithms 2018, 11(8), 114;
Received: 10 July 2018 / Revised: 23 July 2018 / Accepted: 26 July 2018 / Published: 28 July 2018
PDF [557 KB, uploaded 31 July 2018]


The steady growth of the Protein Data Bank (PDB) suggests the periodic repetition of searches for sequences that form different secondary structures in different protein structures; these are called chameleon sequences. This paper presents a fast (nlog(n)) algorithm for such searches and presents the results on all protein structures in the PDB. The longest such sequence found consists of 20 residues. View Full-Text
Keywords: chameleon sequence; residue propensity; Protein Data Bank chameleon sequence; residue propensity; Protein Data Bank

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Mezei, M. Revisiting Chameleon Sequences in the Protein Data Bank. Algorithms 2018, 11, 114.

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