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Open AccessFeature PaperArticle

Using Central Composite Experimental Design to Optimize the Degradation of Tylosin from Aqueous Solution by Photo-Fenton Reaction

Laboratory for Biomaterials and Transport Phenomena LBMPT, University Yahia Fares, Medea 26000, Algeria
Unité de Développement des Equipements Solaires, UDES/Centre de Développement des Energies Renouvelables, CDER, Bou Ismail, Tipaza 42415, Algeria
Department of Medical Physics and Informatics, University of Szeged, Szeged 6720, Hungary
Department of Applied and Environmental Chemistry, University of Szeged, Szeged 6720, Hungary
Author to whom correspondence should be addressed.
Academic Editor: Naozumi Teramoto
Materials 2016, 9(6), 428;
Received: 18 March 2016 / Revised: 11 April 2016 / Accepted: 24 May 2016 / Published: 30 May 2016
(This article belongs to the Special Issue Advancement of Photocatalytic Materials 2016)
The feasibility of the application of the Photo-Fenton process in the treatment of aqueous solution contaminated by Tylosin antibiotic was evaluated. The Response Surface Methodology (RSM) based on Central Composite Design (CCD) was used to evaluate and optimize the effect of hydrogen peroxide, ferrous ion concentration and initial pH as independent variables on the total organic carbon (TOC) removal as the response function. The interaction effects and optimal parameters were obtained by using MODDE software. The significance of the independent variables and their interactions was tested by means of analysis of variance (ANOVA) with a 95% confidence level. Results show that the concentration of the ferrous ion and pH were the main parameters affecting TOC removal, while peroxide concentration had a slight effect on the reaction. The optimum operating conditions to achieve maximum TOC removal were determined. The model prediction for maximum TOC removal was compared to the experimental result at optimal operating conditions. A good agreement between the model prediction and experimental results confirms the soundness of the developed model. View Full-Text
Keywords: Photo-Fenton; Tylosin; RSM; CCD Photo-Fenton; Tylosin; RSM; CCD
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MDPI and ACS Style

Sarrai, A.E.; Hanini, S.; Merzouk, N.K.; Tassalit, D.; Szabó, T.; Hernádi, K.; Nagy, L. Using Central Composite Experimental Design to Optimize the Degradation of Tylosin from Aqueous Solution by Photo-Fenton Reaction. Materials 2016, 9, 428.

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