µXRF Elemental Mapping of Bioresorbable Magnesium-Based Implants in Bone
AbstractThis study investigated the distribution of the elemental constituents of Mg-based implants at various stages of the degradation process in surrounding bone tissue, with a focus on magnesium (Mg), as the main component of the alloy, and yttrium (Y), due to its potential adverse health effects. The measurements were performed on the implant-bearing thin sections of rat bone in a time series of implant degradation between one and 18 months. Micro X-ray fluorescence analysis (μXRF) with a special spectrometer meeting the requirements for the measurements of low-Z elements was used. It was found that the migration and accumulation behaviour of implant degradation products is element-specific. A sharp decrease in Mg was observed in the immediate vicinity of the interface and no specific accumulation or aggregation of Mg in the adjacent bone tissue was detected. By contrast, Y was found to migrate further into the bone over time and to remain in the tissue even after the complete degradation of the implant. Although the nature of Y accumulations must still be clarified, its potential health impact should be considered. View Full-Text
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Turyanskaya, A.; Rauwolf, M.; Grünewald, T.A.; Meischel, M.; Stanzl-Tschegg, S.; Löffler, J.F.; Wobrauschek, P.; Weinberg, A.M.; Lichtenegger, H.C.; Streli, C. µXRF Elemental Mapping of Bioresorbable Magnesium-Based Implants in Bone. Materials 2016, 9, 811.
Turyanskaya A, Rauwolf M, Grünewald TA, Meischel M, Stanzl-Tschegg S, Löffler JF, Wobrauschek P, Weinberg AM, Lichtenegger HC, Streli C. µXRF Elemental Mapping of Bioresorbable Magnesium-Based Implants in Bone. Materials. 2016; 9(10):811.Chicago/Turabian Style
Turyanskaya, Anna; Rauwolf, Mirjam; Grünewald, Tilman A.; Meischel, Martin; Stanzl-Tschegg, Stefanie; Löffler, Jörg F.; Wobrauschek, Peter; Weinberg, Annelie M.; Lichtenegger, Helga C.; Streli, Christina. 2016. "µXRF Elemental Mapping of Bioresorbable Magnesium-Based Implants in Bone." Materials 9, no. 10: 811.
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