Next Article in Journal
Delocalization of Electrons in Strong Insulators at High Dynamic Pressures
Next Article in Special Issue
Calcium Sulfate with Stearic Acid as an Encouraging Carrier for Reindeer Bone Protein Extract
Previous Article in Journal
Optical Properties of ZnO Nanoparticles Capped with Polymers
Open AccessArticle

In Vivo Corrosion of Two Novel Magnesium Alloys ZEK100 and AX30 and Their Mechanical Suitability as Biodegradable Implants

1
University of Veterinary Medicine Hannover Foundation, Small Animal Clinic, Buenteweg 9, 30559 Hannover, Germany
2
Institute of Materials Science, Hannover Center for Production Technology, University of Hannover, An der Universität 2, 30823 Garbsen, Germany
3
Department of Orthopedics, Hannover Medical School, Anna-von-Borries Straße 11, 30167 Hannover, Germany
4
Clinic for Small Animal Surgery and Reproduction, Centre of Clinical Veterinary Medicine, Faculty of Veterinary Medicine, Ludwig-Maximilians-Universitaet Muenchen, Veterinaerstr. 13, 80539 Muenchen, Germany
*
Author to whom correspondence should be addressed.
Materials 2011, 4(6), 1144-1167; https://doi.org/10.3390/ma4061144
Received: 17 May 2011 / Accepted: 15 June 2011 / Published: 21 June 2011
(This article belongs to the Special Issue Orthopaedic Biomaterials)
In magnesium alloys, the components used modify the alloy properties. For magnesium implants in contact with bone, rare earths alloys are commonly examined. These were shown to have a higher corrosion resistance than other alloys and a high mechanical strength, but their exact composition is hard to predict. Therefore a reduction of their content could be favorable. The alloys ZEK100 and AX30 have a reduced content or contain no rare earths at all. The aim of the study was to investigate their in vivo degradation and to assess the suitability of the in vivo µCT for the examination of their corrosion. Implants were inserted in rabbit tibiae. Clinical examinations, X-rays and in vivo µCT scans were done regularly. Afterwards implants were analyzed with REM, electron dispersive X-ray (EDX), weighing and mechanical testing. The in vivo µCT is of great advantage, because it allows a quantification of the corrosion rate and qualitative 3D assessment of the corrosion morphology. The location of the implant has a remarkable effect on the corrosion rate. Due to its mechanical characteristics and its corrosion behavior, ZEK100 was judged to be suitable, while AX30, which displays favorable degradation behavior, has too little mechanical strength for applications in weight bearing bones. View Full-Text
Keywords: biodegradation; magnesium alloy; mechanical stability; animal model; µ computed tomography biodegradation; magnesium alloy; mechanical stability; animal model; µ computed tomography
Show Figures

Figure 1

MDPI and ACS Style

Huehnerschulte, T.A.; Angrisani, N.; Rittershaus, D.; Bormann, D.; Windhagen, H.; Meyer-Lindenberg, A. In Vivo Corrosion of Two Novel Magnesium Alloys ZEK100 and AX30 and Their Mechanical Suitability as Biodegradable Implants. Materials 2011, 4, 1144-1167.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop