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Open AccessReview

Biocompatibility of Different Nerve Tubes

1
Department of Plastic, Reconstructive and Hand Surgery, University of Luebeck, 23538 Luebeck, Germany
2
Institute of Biochemistry and Cell Biology, University of Magdeburg, 39120 Magdeburg, Germany
3
Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Klinikum Bielefeld-Mitte, 33604 Bielefeld, Germany
*
Author to whom correspondence should be addressed.
Materials 2009, 2(4), 1480-1507; https://doi.org/10.3390/ma2041480
Received: 27 August 2009 / Revised: 24 September 2009 / Accepted: 25 September 2009 / Published: 30 September 2009
(This article belongs to the Special Issue Biocompatibility of Materials)
Bridging nerve gaps with suitable grafts is a major clinical problem. The autologous nerve graft is considered to be the gold standard, providing the best functional results; however, donor site morbidity is still a major disadvantage. Various attempts have been made to overcome the problems of autologous nerve grafts with artificial nerve tubes, which are “ready-to-use” in almost every situation. A wide range of materials have been used in animal models but only few have been applied to date clinically, where biocompatibility is an inevitable prerequisite. This review gives an idea about artificial nerve tubes with special focus on their biocompatibility in animals and humans. View Full-Text
Keywords: nerve tube; nerve repair; biocompatibility; artificial nerve; peripheral nerve nerve tube; nerve repair; biocompatibility; artificial nerve; peripheral nerve
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Stang, F.; Keilhoff, G.; Fansa, H. Biocompatibility of Different Nerve Tubes. Materials 2009, 2, 1480-1507.

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