Next Article in Journal
Turning Tissue Waste into High-Performance Microfiber Filters for Oily Wastewater Treatment
Previous Article in Journal
Enzymatic Degradation of Acrylic Acid-Grafted Poly(butylene succinate-co-terephthalate) Nanocomposites Fabricated Using Heat Pressing and Freeze-Drying Techniques
Previous Article in Special Issue
Releasing Behavior of Lipopolysaccharide from Gelatin Modulates Inflammation, Cellular Senescence, and Bone Formation in Critical-Sized Bone Defects in Rat Calvaria
Open AccessArticle

Effect of the Application of a Dehydrothermal Treatment on the Structure and the Mechanical Properties of Collagen Film

1
Department of Biobased Materials Science, Kyoto Institute of Technology, Kyoto 606-8585, Japan
2
Textile Research Institute of Gunma, Gunma 376-0011, Japan
3
Nitta Gelatin Inc., Osaka 581-0024, Japan
*
Author to whom correspondence should be addressed.
Materials 2020, 13(2), 377; https://doi.org/10.3390/ma13020377
Received: 18 December 2019 / Revised: 8 January 2020 / Accepted: 10 January 2020 / Published: 14 January 2020
(This article belongs to the Special Issue Biobased Polymers)
Dehydrothermal (DHT) treatment was used to improve the properties of collagen casings because of its non-cytotoxicity. Understanding the effects of DHT treatment on the structure and mechanical properties of collagen films is beneficial to developing satisfying collagen casings. Herein, DHT treatment with various temperatures (85–145 °C) and timescales (1–7 days) were investigated. It was clarified that the chemical crosslinking covalent bond between collagen molecules was formed after the DHT treatment. Crosslinking density increased with increasing DHT treatment temperatures, contributing to the increase of tensile strength up to over three times of that of the untreated collagen film. The increased crosslinking density was also found when increasing the DHT treatment time, and the maximum was obtained in 3 days. Further DHT treatment time did not change the crosslinking density. The damage in the triple helix structure and the self-assembly of collagen molecules were observed from IR and SAXS. The extent of denaturation increased with increasing DHT treatment temperature and time, although the effect of the DHT treatment time on the denaturation was more moderate. When the DHT treatment temperature was as high as 145 °C or the DHT treatment time exceeded 5 days, serious denaturation occurs, leading to the deterioration of mechanical properties. View Full-Text
Keywords: collagen film; dehydrothermal treatment; crosslinking; denaturation; mechanical property; structure collagen film; dehydrothermal treatment; crosslinking; denaturation; mechanical property; structure
Show Figures

Figure 1

MDPI and ACS Style

Chen, X.; Zhou, L.; Xu, H.; Yamamoto, M.; Shinoda, M.; Kishimoto, M.; Tanaka, T.; Yamane, H. Effect of the Application of a Dehydrothermal Treatment on the Structure and the Mechanical Properties of Collagen Film. Materials 2020, 13, 377.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop