Overview of Carbon Nanotubes for Biomedical Applications
CIRIMAT, Université Toulouse Paul Sabatier, B.t. CIRIMAT, 118 route de Narbonne, 31062 Toulouse CEDEX 9, France
Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse Paul Sabatier, 205, Route de Narbonne, 31077 Toulouse CEDEX 4, France
Authors to whom correspondence should be addressed.
Materials 2019, 12(4), 624; https://doi.org/10.3390/ma12040624
Received: 16 January 2019 / Revised: 8 February 2019 / Accepted: 14 February 2019 / Published: 20 February 2019
(This article belongs to the Special Issue Inorganic Nanoparticles for Targeted Therapy: Fabrication, Physical Properties, Biomedical Applications and Fate)
The unique combination of mechanical, optical and electrical properties offered by carbon nanotubes has fostered research for their use in many kinds of applications, including the biomedical field. However, due to persisting outstanding questions regarding their potential toxicity when considered as free particles, the research is now focusing on their immobilization on substrates for interface tuning or as biosensors, as load in nanocomposite materials where they improve both mechanical and electrical properties or even for direct use as scaffolds for tissue engineering. After a brief introduction to carbon nanotubes in general and their proposed applications in the biomedical field, this review will focus on nanocomposite materials with hydrogel-based matrices and especially their potential future use for diagnostics, tissue engineering or targeted drug delivery. The toxicity issue will also be briefly described in order to justify the safe(r)-by-design approach offered by carbon nanotubes-based hydrogels.