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Open AccessReview

Phosphorene Is the New Graphene in Biomedical Applications

1
Marrelli Health—Tecnologica Research Institute, Biomedical Section, Street E. Fermi, 88900 Crotone, Italy
2
Department of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia
3
Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola (RA), Italy
4
Department of Biomedical Sciences, University of Padova, 35100 Padova, Italy
5
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Napoli Federico II, 80131 Naples, Italy
6
Department of Health Sciences, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy
*
Author to whom correspondence should be addressed.
These authors equally contributed to the work.
Materials 2019, 12(14), 2301; https://doi.org/10.3390/ma12142301
Received: 21 June 2019 / Revised: 9 July 2019 / Accepted: 16 July 2019 / Published: 18 July 2019
(This article belongs to the Special Issue Bio-Inspired Materials for Biomedical Applications)
Nowadays, the research of smart materials is focusing on the allotropics, which have specific characteristics that are useful in several areas, including biomedical applications. In recent years, graphene has revealed interesting antibacterial and physical peculiarities, but it has also shown limitations. Black phosphorus has structural and biochemical properties that make it ideal for biomedical applications: 2D sheets of black phosphorus are called Black Phosphorene (BP), and it could replace graphene in the coming years. BP, similar to other 2D materials, can be used for colorimetric and fluorescent detectors, as well as for biosensing devices. BP also shows high in vivo biodegradability, producing non-toxic agents in the body. This characteristic is promising for pharmacological applications, as well as for scaffold and prosthetic coatings. BP shows low cytotoxicity, thus avoiding the induction of local inflammation or toxicity. As such, BP is a good candidate for different applications in the biomedical sector. Properties such as biocompatibility, biodegradability, and biosafety are essential for use in medicine. In this review, we have exploited all such aspects, also comparing BP with other similar materials, such as the well-known graphene. View Full-Text
Keywords: biomaterials; bone tissue; biomedical applications biomaterials; bone tissue; biomedical applications
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MDPI and ACS Style

Tatullo, M.; Genovese, F.; Aiello, E.; Amantea, M.; Makeeva, I.; Zavan, B.; Rengo, S.; Fortunato, L. Phosphorene Is the New Graphene in Biomedical Applications. Materials 2019, 12, 2301. https://doi.org/10.3390/ma12142301

AMA Style

Tatullo M, Genovese F, Aiello E, Amantea M, Makeeva I, Zavan B, Rengo S, Fortunato L. Phosphorene Is the New Graphene in Biomedical Applications. Materials. 2019; 12(14):2301. https://doi.org/10.3390/ma12142301

Chicago/Turabian Style

Tatullo, Marco; Genovese, Fabio; Aiello, Elisabetta; Amantea, Massimiliano; Makeeva, Irina; Zavan, Barbara; Rengo, Sandro; Fortunato, Leonzio. 2019. "Phosphorene Is the New Graphene in Biomedical Applications" Materials 12, no. 14: 2301. https://doi.org/10.3390/ma12142301

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