Next Article in Journal
Thermomechanical Studies of Yielding and Strain Localization Phenomena of Gum Metal under Tension
Next Article in Special Issue
Fabrication and Characterization of an Electrospun PHA/Graphene Silver Nanocomposite Scaffold for Antibacterial Applications
Previous Article in Journal
Load-Bearing Capacity and Retention of Newly Developed Micro-Locking Implant Prosthetic System: An In Vitro Pilot Study
Open AccessFeature PaperArticle

Nano-Graphene Oxide Functionalized Bioactive Poly(lactic acid) and Poly(ε-caprolactone) Nanofibrous Scaffolds

1
Department of Fibre and Polymer Technology, KTH Royal Institute of Technology, SE-100 44 Stockholm, Sweden
2
Department of Textile Technology, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India
*
Author to whom correspondence should be addressed.
Materials 2018, 11(4), 566; https://doi.org/10.3390/ma11040566
Received: 27 January 2018 / Revised: 22 March 2018 / Accepted: 5 April 2018 / Published: 6 April 2018
(This article belongs to the Special Issue Graphene in Biomedical Application)
A versatile and convenient way to produce bioactive poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) electrospun nanofibrous scaffolds is described. PLA and PCL are extensively used as biocompatible scaffold materials for tissue engineering. Here, biobased nano graphene oxide dots (nGO) are incorporated in PLA or PCL electrospun scaffolds during the electrospinning process aiming to enhance the mechanical properties and endorse osteo-bioactivity. nGO was found to tightly attach to the fibers through secondary interactions. It also improved the electrospinnability and fiber quality. The prepared nanofibrous scaffolds exhibited enhanced mechanical properties, increased hydrophilicity, good cytocompatibility and osteo-bioactivity. Therefore, immense potential for bone tissue engineering applications is anticipated. View Full-Text
Keywords: PLA; PCL; graphene oxide; scaffold; mechanical properties; biomineralization PLA; PCL; graphene oxide; scaffold; mechanical properties; biomineralization
Show Figures

Graphical abstract

MDPI and ACS Style

Wu, D.; Samanta, A.; Srivastava, R.K.; Hakkarainen, M. Nano-Graphene Oxide Functionalized Bioactive Poly(lactic acid) and Poly(ε-caprolactone) Nanofibrous Scaffolds. Materials 2018, 11, 566.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop