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Materials 2017, 10(12), 1372;

Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy

The Key Laboratory of Resource Chemistry of the Ministry of Education, the Shanghai Key Laboratory of Rare Earth Functional Materials, and the Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Normal University, Shanghai 200234, China
Authors to whom correspondence should be addressed.
Received: 20 October 2017 / Revised: 16 November 2017 / Accepted: 25 November 2017 / Published: 30 November 2017
(This article belongs to the Section Biomaterials)
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Over the past few decades, the synthetic development of ultra-small nanoparticles has become an important strategy in nano-medicine, where smaller-sized nanoparticles are known to be more easily excreted from the body, greatly reducing the risk caused by introducing nano-theranostic agents. Gold nanorods are one of the most important nano-theranostic agents because of their special optical and electronic properties. However, the large size (diameter > 6 nm) of most obtained gold nanorods limits their clinical application. In recent years, more and more researchers have begun to investigate the synthesis and application of small gold nanorods (diameter < 6 nm), which exhibit similar optical and electronic properties as larger gold nanorods. In this review, we summarize the recent advances of synthesis of the small gold nanorods and their application for near-infrared light-mediated bio-imaging and cancer therapy. View Full-Text
Keywords: small gold nanorods; seedless; biological imaging; cancer therapy small gold nanorods; seedless; biological imaging; cancer therapy

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An, L.; Wang, Y.; Tian, Q.; Yang, S. Small Gold Nanorods: Recent Advances in Synthesis, Biological Imaging, and Cancer Therapy. Materials 2017, 10, 1372.

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