Trends in Selective Internal Radiation Therapy (SIRT) for Treating Hepatocellular Carcinoma, Cholangiocarcinoma, and Liver Metastasis: A Total Population Analysis from 2006 to 2021 in Germany
Abstract
:1. Introduction
2. Materials and Methods
2.1. Database
2.2. German Billing Database (Destatis)
2.3. German Hospitals’ Quality Reports
2.4. Statistical Analysis
2.5. Ethics Statement
3. Results
4. Discussion
4.1. HCC, CCC, and Liver Metastasis
4.2. Patient’s Age, Caseload Distribution, and University Setting
4.3. In-Hospital Complications and Mortality, Blood Transfusions, and LOS
4.4. Holmium, Rhenium, and Yttrium
4.5. Limitations and Strengths
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Source of data | Nationwide hospital billing database of the German Federal Statistical Office (Destatis database) | German hospitals’ quality reports (reimbursement.INFO tool) |
Details | Age and gender Diagnosis code in combination with OPS code Surgical access route Hospital characteristics (teaching status, size, annual surgery/procedure caseload, approaches for surgery/procedure) | Age and gender Diagnosis code or OPS code (no combination possible) Hospital characteristics (teaching status, annual surgery/procedure caseload) Geographical localization of respective hospitals |
Number of patients | 13,981 | 14,165 |
Proportion of population | 100% | 100% |
Years | 2006–2019 | 2008–2021 (missing: 2006, 2007, 2009, 2011) |
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© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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Thoduka, S.G.; Flegar, L.; Groeben, C.; Huber, J.; Eisenmenger, N.; Paulus, T.; Vogt, K.; Luster, M.; Abolmaali, N. Trends in Selective Internal Radiation Therapy (SIRT) for Treating Hepatocellular Carcinoma, Cholangiocarcinoma, and Liver Metastasis: A Total Population Analysis from 2006 to 2021 in Germany. Curr. Oncol. 2023, 30, 10325-10335. https://doi.org/10.3390/curroncol30120752
Thoduka SG, Flegar L, Groeben C, Huber J, Eisenmenger N, Paulus T, Vogt K, Luster M, Abolmaali N. Trends in Selective Internal Radiation Therapy (SIRT) for Treating Hepatocellular Carcinoma, Cholangiocarcinoma, and Liver Metastasis: A Total Population Analysis from 2006 to 2021 in Germany. Current Oncology. 2023; 30(12):10325-10335. https://doi.org/10.3390/curroncol30120752
Chicago/Turabian StyleThoduka, Smita George, Luka Flegar, Christer Groeben, Johannes Huber, Nicole Eisenmenger, Tobias Paulus, Katharina Vogt, Markus Luster, and Nasreddin Abolmaali. 2023. "Trends in Selective Internal Radiation Therapy (SIRT) for Treating Hepatocellular Carcinoma, Cholangiocarcinoma, and Liver Metastasis: A Total Population Analysis from 2006 to 2021 in Germany" Current Oncology 30, no. 12: 10325-10335. https://doi.org/10.3390/curroncol30120752
APA StyleThoduka, S. G., Flegar, L., Groeben, C., Huber, J., Eisenmenger, N., Paulus, T., Vogt, K., Luster, M., & Abolmaali, N. (2023). Trends in Selective Internal Radiation Therapy (SIRT) for Treating Hepatocellular Carcinoma, Cholangiocarcinoma, and Liver Metastasis: A Total Population Analysis from 2006 to 2021 in Germany. Current Oncology, 30(12), 10325-10335. https://doi.org/10.3390/curroncol30120752