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Volume 30
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Article

Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes

by
Carmelina C. Zirafa
1,*,
Gaetano Romano
1,
Elisa Sicolo
1,
Elena Bagalà
1,
Beatrice Manfredini
2,
Greta Alì
3,
Andrea Castaldi
1,
Riccardo Morganti
4,
Federico Davini
1,
Gabriella Fontanini
3 and
Franca Melfi
1
1
Minimally Invasive and Robotic Thoracic Surgery, Surgical, Medical, Molecular, and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy
2
Division of Thoracic Surgery, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, 41121 Modena, Italy
3
Pathological Anatomy, Surgical, Medical, Molecular, and Critical Care Pathology Department, University Hospital of Pisa, 56124 Pisa, Italy
4
Section of Statistics, University Hospital of Pisa, 56124 Pisa, Italy
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2023, 30(10), 9104-9115; https://doi.org/10.3390/curroncol30100658
Submission received: 31 August 2023 / Revised: 6 October 2023 / Accepted: 11 October 2023 / Published: 12 October 2023
(This article belongs to the Section Thoracic Oncology)
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Abstract

Locally advanced non-small cell lung cancer (NSCLC) consists of a heterogeneous group, with different pulmonary extension and lymph nodal involvement. Robotic surgery can play a key role in these tumours thanks to its technological features, although open surgery is still considered the gold-standard approach. Our study aims to evaluate the surgical and oncological outcomes of locally advanced NSCLC patients who underwent robotic surgery in a high-volume centre. Data from consecutive patients with locally advanced NSCLC who underwent robotic lobectomy were retrospectively analysed and compared with patients treated with open surgery. Clinical characteristics and surgical and oncological information were evaluated. From 2010 to 2020, 131 patients underwent anatomical lung resection for locally advanced NSCLC. A total of 61 patients were treated with robotic surgery (46.6%); the median hospitalization time was 5.9 days (range 2–27) and the postoperative complication rate was 18%. Open surgery was performed in 70 patients (53.4%); the median length of stay was 9 days (range 4–48) and the postoperative complication rate was 22.9%. The median follow-up time was 70 months. The 5-year overall survival was 34% in the robotic group and 31% in the thoracotomy group. Robotic surgery can be considered safe and feasible not only for early stages but also for the treatment of locally advanced NSCLC.
Keywords: locally advanced non-small cell lung cancer; NSCLC; robotic surgery; minimally invasive surgery (MIS); surgical results; oncological outcomes locally advanced non-small cell lung cancer; NSCLC; robotic surgery; minimally invasive surgery (MIS); surgical results; oncological outcomes
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MDPI and ACS Style

Zirafa, C.C.; Romano, G.; Sicolo, E.; Bagalà, E.; Manfredini, B.; Alì, G.; Castaldi, A.; Morganti, R.; Davini, F.; Fontanini, G.; et al. Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes. Curr. Oncol. 2023, 30, 9104-9115. https://doi.org/10.3390/curroncol30100658

AMA Style

Zirafa CC, Romano G, Sicolo E, Bagalà E, Manfredini B, Alì G, Castaldi A, Morganti R, Davini F, Fontanini G, et al. Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes. Current Oncology. 2023; 30(10):9104-9115. https://doi.org/10.3390/curroncol30100658

Chicago/Turabian Style

Zirafa, Carmelina C., Gaetano Romano, Elisa Sicolo, Elena Bagalà, Beatrice Manfredini, Greta Alì, Andrea Castaldi, Riccardo Morganti, Federico Davini, Gabriella Fontanini, and et al. 2023. "Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes" Current Oncology 30, no. 10: 9104-9115. https://doi.org/10.3390/curroncol30100658

APA Style

Zirafa, C. C., Romano, G., Sicolo, E., Bagalà, E., Manfredini, B., Alì, G., Castaldi, A., Morganti, R., Davini, F., Fontanini, G., & Melfi, F. (2023). Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes. Current Oncology, 30(10), 9104-9115. https://doi.org/10.3390/curroncol30100658

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