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Current Oncology
Volume 29
Issue 10
10.3390/curroncol29100536
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Review
Peer-Review Record

Diagnosis, Treatment and Prognosis of Primary Pulmonary NUT Carcinoma: A Literature Review

Curr. Oncol. 2022, 29(10), 6807-6815; https://doi.org/10.3390/curroncol29100536
by Jiaqian Yuan 1, Zhili Xu 2 and Yong Guo 2,*
Reviewer 1: Anonymous
Reviewer 2:
Arpita Rai
Curr. Oncol. 2022, 29(10), 6807-6815; https://doi.org/10.3390/curroncol29100536
Submission received: 25 July 2022 / Revised: 13 September 2022 / Accepted: 19 September 2022 / Published: 22 September 2022

Round 1

Reviewer 1 Report

 

Jiaqian Yuan and Yong Guo present the manuscript entitled “Diagnosis, Treatment And Prognosis Of Primary Pulmonary NUT Carcinoma: A literature review”.

Major Points:

1. Although the manuscript clearly indicates that its oriented to review the Diagnosis, Treatment And Prognosis Of Primary Pulmonary 2NUT Carcinoma, molecular features of this rare type of cancer should be very informative for non-experts readers. Please add a new section reviewing the genetics/ genomics and molecular biology of 2NUT carcinoma.

2. In general, there are many typos and orthographical errors and the English should be thoroughly revised.

3. The authors should discuss, what is the main relevance of this review?

Minor comments:

Introduction

Page 1, line 30 Replace “testis(NUT)” with “testis (NUT)”.

Page 1, line 30 Replace “its” with “it´s”.

The authors should rewrite the introduction as it is very brief and has several typographical errors.

Results

Authors should include a table with clinical characteristics.

Page 2, line 81. Delete the extra period.

Page 2, line 75. Add a space between the word and the opening bracket.

 

Discussion

The authors should more deeply discuss the results.

Author Response

Thanks for your comments. Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

The work of the authors is appreciated, as the topic seems to be unique and relevant. The representation of the information regarding NUT Carcinoma is good. I would like to share some suggestions for the improvement of the manuscript.

Result:

*Explain the meaning of "M (P25, P75)=36 (26,54)" in section 3.1

Discussion:

*Define unusual abbreviations e.g. CTX, IFO.

*It will be better if the author adds a conclusive sentence about NC disease characteristics, diagnosis, and management.

Author Response

Thanks for your comments. Please see the attachment.

Author Response File: Author Response.docx

Round 2

Reviewer 1 Report

Authors have replied all my concerns, thus I strongly suggest to accept the manuscript for publication in its actual form.

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