Next Article in Journal
Implementation of the Canadian National Standards in Breast Cancer Surgical Care: Gaps, Barriers, Enablers and Opportunities
Previous Article in Journal
Clinicopathologic and Treatment Features of Long-Term Surviving Brain Metastasis Patients
Open AccessCase Report

A Rare Coexistence of Paraneoplastic Cerebellar Degeneration: Papillary Thyroid Carcinoma

Eskisehir City Hospital, Department of Neurology, Eskisehir 26080, Turkey
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2021, 28(1), 560-564; https://doi.org/10.3390/curroncol28010055
Received: 18 November 2020 / Revised: 16 December 2020 / Accepted: 30 December 2020 / Published: 19 January 2021
Paraneoplastic cerebellar degeneration (PCD) is a rare neuroimmunological disease that may accompany tumors. In this article, we present a patient with progressive gait difficulty who was diagnosed with PCD and, in a rare comorbidity, with papillary thyroid carcinoma (PTC) following malignancy screening. A 46-year-old male patient reported having experienced poor balance for 2 years. A neurological examination revealed nystagmus, intention tremor, and ataxia, and anti-thyroid peroxidase and anti-thyroglobulin levels were found to be elevated. A brain MRI showed significant cerebellar atrophy in the superior vermis. Malignancy screening for PCD was performed, and thyroid ultrasonography revealed a nodule in the left lobe, while PET/CT detected elevated focal F-18 fluorodeoxyglucose uptake in the thyroid. Onconeuronal antibodies (anti-Hu, anti-Yo, anti-Ri, anti-amphiphysin, anti-Tr, anti-PPCA-2, anti-Ma, anti-CV-1, and anti-ANNA-3) were negative. Pathologic examination of the thyroid revealed PTC, for which the patient was treated with 0.4 g/kg intravenous immunoglobulin and referred to the medical oncology department. This case demonstrates that clinicians must be alert to the rare comorbidity of PCD and PTC. View Full-Text
Keywords: paraneoplastic cerebellar degeneration; ataxia; papillary thyroid carcinoma paraneoplastic cerebellar degeneration; ataxia; papillary thyroid carcinoma
Show Figures

Figure 1

MDPI and ACS Style

Ayas, Z.Ö.; Uncu, G. A Rare Coexistence of Paraneoplastic Cerebellar Degeneration: Papillary Thyroid Carcinoma. Curr. Oncol. 2021, 28, 560-564. https://doi.org/10.3390/curroncol28010055

AMA Style

Ayas ZÖ, Uncu G. A Rare Coexistence of Paraneoplastic Cerebellar Degeneration: Papillary Thyroid Carcinoma. Current Oncology. 2021; 28(1):560-564. https://doi.org/10.3390/curroncol28010055

Chicago/Turabian Style

Ayas, Zeynep Ö.; Uncu, Gülgün. 2021. "A Rare Coexistence of Paraneoplastic Cerebellar Degeneration: Papillary Thyroid Carcinoma" Curr. Oncol. 28, no. 1: 560-564. https://doi.org/10.3390/curroncol28010055

Find Other Styles

Article Access Map by Country/Region

1
Back to TopTop