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Article

Should Laparoscopic Lymph Node Biopsy Be the Preferred Diagnostic Modality for Isolated Abdominal Lymphadenopathy?

by
R.W.D. Gilbert
1,2,*,
B.H. Bird
1,3,
M.G. Murphy
1,4 and
C.J. O’Boyle
1,5
1
School of Medicine, University College Cork, Cork, Ireland
2
Department of General Surgery, University of Ottawa, Ottawa, ON, Canada
3
Department of Haematology and Oncology, Bon Secours Hospital, Cork, Ireland
4
Department of Diagnostic and Interventional Radiology, Bon Secours Hospital, Cork, Ireland
5
Department of Surgery, Bon Secours Hospital, Cork, Ireland
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2019, 26(3), 341-345; https://doi.org/10.3747/co.26.4170
Submission received: 7 March 2019 / Revised: 7 April 2019 / Accepted: 7 May 2019 / Published: 1 June 2019

Abstract

Background: Isolated abdominal lymphadenopathy is frequently detected, but often challenging to diagnose. To obtain a tissue diagnosis, percutaneous biopsy (PB) or laparoscopic biopsy (LB) is often undertaken. The safety profiles and diagnostic accuracy of PB and LB within the abdomen are both poorly defined. Methods: In this retrospective analysis, we identified all patients who underwent LB or PB for isolated abdominal lymphadenopathy at our institute during 2008–2016. Results: Of 62 patients who underwent nodal biopsy for isolated abdominal lymphadenopathy, 33 underwent LB and 29 underwent PB. For the 33 patients who underwent LB, the procedure was diagnostic in 100% of cases; for the 29 who underwent PB, the procedure was diagnostic in 18 cases (62.1%). Both procedures were safe, with similar complication rates (6.0% for LB; 7.0% for PB). Conclusions: Our results establish that LB and PB are both safe and reliable in the setting of isolated abdominal lymphadenopathy. We also demonstrate that each procedure has situational advantages. A PB should be considered to be the upfront diagnostic modality, particularly when anatomic or disease factors favour its success. In situations in which it is felt that PB cannot safely access the lymphadenopathy or in disease states in which the yield of a core biopsy will be insufficient, LB should be strongly considered. Examples include extra-retroperitoneal lymphadenopathy and cases of suspected lymphoma.
Keywords: biopsies; laparoscopy; lymph nodes; lymphoma; medical oncology; surgical oncology biopsies; laparoscopy; lymph nodes; lymphoma; medical oncology; surgical oncology

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MDPI and ACS Style

Gilbert, R.W.D.; Bird, B.H.; Murphy, M.G.; O’Boyle, C.J. Should Laparoscopic Lymph Node Biopsy Be the Preferred Diagnostic Modality for Isolated Abdominal Lymphadenopathy? Curr. Oncol. 2019, 26, 341-345. https://doi.org/10.3747/co.26.4170

AMA Style

Gilbert RWD, Bird BH, Murphy MG, O’Boyle CJ. Should Laparoscopic Lymph Node Biopsy Be the Preferred Diagnostic Modality for Isolated Abdominal Lymphadenopathy? Current Oncology. 2019; 26(3):341-345. https://doi.org/10.3747/co.26.4170

Chicago/Turabian Style

Gilbert, R.W.D., B.H. Bird, M.G. Murphy, and C.J. O’Boyle. 2019. "Should Laparoscopic Lymph Node Biopsy Be the Preferred Diagnostic Modality for Isolated Abdominal Lymphadenopathy?" Current Oncology 26, no. 3: 341-345. https://doi.org/10.3747/co.26.4170

APA Style

Gilbert, R. W. D., Bird, B. H., Murphy, M. G., & O’Boyle, C. J. (2019). Should Laparoscopic Lymph Node Biopsy Be the Preferred Diagnostic Modality for Isolated Abdominal Lymphadenopathy? Current Oncology, 26(3), 341-345. https://doi.org/10.3747/co.26.4170

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