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Article

A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy

1
Department of Medical Physics, BC Cancer–Fraser Valley Centre, 13750 96th Avenue, Surrey, BC V3V 1Z2, Canada
2
Brody School of Medicine, East Carolina University, Greenville, NC, USA
3
School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2018, 25(3), 193-199; https://doi.org/10.3747/co.25.3920
Submission received: 2 March 2018 / Revised: 4 April 2018 / Accepted: 5 May 2018 / Published: 1 June 2018

Abstract

Malnutrition is a frequent manifestation in patients with head-and-neck cancer undergoing radiation therapy and a major contributor to morbidity and mortality. Thus, body composition is an important component of an overall evaluation of nutrition in cancer patients. Malnutrition is characterized by weight loss, loss of muscle mass, changes in cell membrane integrity, and alterations in fluid balance. Bioelectrical impedance analysis is a method to analyze body composition and includes parameters such as intracellular water content, extracellular water content, and cell membrane integrity in the form of a phase angle (Φ). Bioelectrical impedance analysis has consistently been shown to have prognostic value with respect to mortality and morbidity in patients undergoing chemotherapy. The goal of the present study was to evaluate the relationship between Φ, time, intracellular water content, and weight for head-and-neck cancer patients undergoing radiotherapy. The results demonstrate that Φ decreases with time and increases with intracellular water content and weight.
Keywords: head-and-neck cancer; radiation therapy; bioimpedance analysis; phase angle; intracellular water; extracellular water; malnutrition head-and-neck cancer; radiation therapy; bioimpedance analysis; phase angle; intracellular water; extracellular water; malnutrition

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MDPI and ACS Style

Kohli, K.; Corns, R.; Vinnakota, K.; Steiner, P.; Elith, C.; Schellenberg, D.; Kwan, W.; Karvat, A. A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy. Curr. Oncol. 2018, 25, 193-199. https://doi.org/10.3747/co.25.3920

AMA Style

Kohli K, Corns R, Vinnakota K, Steiner P, Elith C, Schellenberg D, Kwan W, Karvat A. A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy. Current Oncology. 2018; 25(3):193-199. https://doi.org/10.3747/co.25.3920

Chicago/Turabian Style

Kohli, K., R. Corns, K. Vinnakota, P. Steiner, C. Elith, D. Schellenberg, W. Kwan, and A. Karvat. 2018. "A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy" Current Oncology 25, no. 3: 193-199. https://doi.org/10.3747/co.25.3920

APA Style

Kohli, K., Corns, R., Vinnakota, K., Steiner, P., Elith, C., Schellenberg, D., Kwan, W., & Karvat, A. (2018). A Bioimpedance Analysis of Head-and-neck Cancer Patients Undergoing Radiotherapy. Current Oncology, 25(3), 193-199. https://doi.org/10.3747/co.25.3920

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