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Current Oncology
Volume 21
Issue 2
10.3747/co.21.1844
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Localized Synchronous Squamous Cell Carcinomas of the Esophagus and Hypopharynx Treated with Definitive Concurrent Chemoradiotherapy with a Unified Radiotherapy Plan

by
J.B. Wallach
*,
M.M. Rosenstein
and
S. Kalnicki
Department of Radiation Oncology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, USA
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2014, 21(2), 354-357; https://doi.org/10.3747/co.21.1844
Submission received: 3 January 2014 / Revised: 5 February 2014 / Accepted: 10 March 2014 / Published: 1 April 2014

Abstract

Because of common risk factors, synchronous squamous cell carcinomas of the esophagus and head and neck are common, and their concurrent presence can significantly complicate disease eradication and survival. Here, we report the case of a patient with a history of extensive tobacco and alcohol use who was diagnosed with a localized thoracic esophageal squamous cell carcinoma, and in whom positron-emission tomography–computed tomography discovered a nearby asymptomatic localized hypopharyngeal focus that was confirmed by biopsy to also be malignant. He was treated with definitive concurrent chemoradiotherapy in a single unified radiotherapy plan, with surgery reserved for salvage treatment. He currently remains in remission without a need for surgical salvage. However, significant concern remains for both treatment failure and development of another primary because of “field cancerization.”
Keywords: synchronous squamous cell carcinomas; esophageal cancer; hypopharyngeal cancer; chemotherapy; radiotherapy; field cancerization synchronous squamous cell carcinomas; esophageal cancer; hypopharyngeal cancer; chemotherapy; radiotherapy; field cancerization

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MDPI and ACS Style

Wallach, J.B.; Rosenstein, M.M.; Kalnicki, S. Localized Synchronous Squamous Cell Carcinomas of the Esophagus and Hypopharynx Treated with Definitive Concurrent Chemoradiotherapy with a Unified Radiotherapy Plan. Curr. Oncol. 2014, 21, 354-357. https://doi.org/10.3747/co.21.1844

AMA Style

Wallach JB, Rosenstein MM, Kalnicki S. Localized Synchronous Squamous Cell Carcinomas of the Esophagus and Hypopharynx Treated with Definitive Concurrent Chemoradiotherapy with a Unified Radiotherapy Plan. Current Oncology. 2014; 21(2):354-357. https://doi.org/10.3747/co.21.1844

Chicago/Turabian Style

Wallach, J.B., M.M. Rosenstein, and S. Kalnicki. 2014. "Localized Synchronous Squamous Cell Carcinomas of the Esophagus and Hypopharynx Treated with Definitive Concurrent Chemoradiotherapy with a Unified Radiotherapy Plan" Current Oncology 21, no. 2: 354-357. https://doi.org/10.3747/co.21.1844

APA Style

Wallach, J. B., Rosenstein, M. M., & Kalnicki, S. (2014). Localized Synchronous Squamous Cell Carcinomas of the Esophagus and Hypopharynx Treated with Definitive Concurrent Chemoradiotherapy with a Unified Radiotherapy Plan. Current Oncology, 21(2), 354-357. https://doi.org/10.3747/co.21.1844

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