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Article

Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis

1
Adult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland
2
Department of Analytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland
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Department of Analytical and Environmental Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland
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Poznan LAB, Institute of Practical Medicine, 62-081 Przezmierowo, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Michaël R. Laurent
Int. J. Environ. Res. Public Health 2021, 18(6), 3260; https://doi.org/10.3390/ijerph18063260
Received: 28 February 2021 / Revised: 14 March 2021 / Accepted: 20 March 2021 / Published: 22 March 2021
Bone metabolism and the trace element content associated with it change at each stage of degenerative disease. The aim of this study was to find out about the role of the analyzed elements in different stages of hip osteoarthritis. Elements associated with oxidative and enzymatic processes were analyzed depending on the changes in the radiological images of the hip joint. Element content analysis was performed by the inductively coupled plasma mass spectrometry analytical technique. The femoral head in severely osteoarthritic hips (KL3–4) compared to mild grade osteoarthritis (KL2) had a greater content of Cu (median 1.04 vs. 0.04), Sr (median 38.71 vs. 29.59), and Zn (median 75.12 vs. 63.21). There were no significant differences in the content of Mo, Cr, and Fe in the femoral head and neck between the groups. The Cu/Fe correlation was negative in the KL2 group (−0.47) and positive in the KL3–4 groups (0.45). Changes in the content and correlation of trace elements in the hip joint explain the changes in metabolism dependent on the severity of degenerative changes. View Full-Text
Keywords: trace elements; metalloproteinase; femoral bone; hip osteoarthritis stages; grades trace elements; metalloproteinase; femoral bone; hip osteoarthritis stages; grades
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MDPI and ACS Style

Dąbrowski, M.; Zioła-Frankowska, A.; Frankowski, M.; Kaczmarczyk, J.; Kubaszewski, Ł. Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis. Int. J. Environ. Res. Public Health 2021, 18, 3260. https://doi.org/10.3390/ijerph18063260

AMA Style

Dąbrowski M, Zioła-Frankowska A, Frankowski M, Kaczmarczyk J, Kubaszewski Ł. Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis. International Journal of Environmental Research and Public Health. 2021; 18(6):3260. https://doi.org/10.3390/ijerph18063260

Chicago/Turabian Style

Dąbrowski, Mikołaj, Anetta Zioła-Frankowska, Marcin Frankowski, Jacek Kaczmarczyk, and Łukasz Kubaszewski. 2021. "Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis" International Journal of Environmental Research and Public Health 18, no. 6: 3260. https://doi.org/10.3390/ijerph18063260

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