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Article

Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study

1
Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy
2
Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy
3
L’Altrastatistica Consultancy & Training, Biostatistics Office, 00175 Rome, Italy
4
Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari “Aldo Moro”, 70124 Bari, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2021, 18(4), 1488; https://doi.org/10.3390/ijerph18041488
Received: 19 December 2020 / Revised: 20 January 2021 / Accepted: 31 January 2021 / Published: 4 February 2021
(This article belongs to the Special Issue Basics of Hygiene in Public Health and Health Promotion)
At the end of 2019, a new disease caused by the novel coronavirus SARS-CoV-2 appeared in Wuhan Province in China. Children seemed to be infected less frequently than adults, and family clusters seemed to play an important role in the spread of the pandemic. The aim of this study is to evaluate the serological profile of children and young adults between 4 and 16 years of age in order to assess the transmission patterns of COVID-19 between cohabitants. The subjects lived with at least one cohabitant who tested positive for the disease using a nasopharyngeal swab. To avoid contact with the disease, families were interviewed by telephone. Forty-nine children and adolescents with a mean age of 11 years were then subjected to a rapid lateral flow chromatographic test. Of them, seven (14.3%) were immunoglobulin G (IgG)-positive, and four (8.2%) were immunoglobulin M (IgM)-positive. In total, 16.3% of the tested sample had antibodies against SARS-CoV-2: this may confirm the lower vulnerability of children to COVID-19, despite the small sample size. The time from the negativization of the cohabitant until the test day may have influenced the results, especially when this timeframe is wide. View Full-Text
Keywords: COVID-19; SARS-CoV-2; serological test; children; young adults; adolescents; family cluster COVID-19; SARS-CoV-2; serological test; children; young adults; adolescents; family cluster
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MDPI and ACS Style

Farronato, M.; Dolci, C.; Boccalari, E.; Izadi, S.; Salvatierra Rios, L.H.; Festa, M.; Panetta, V.; De Vito, D.; Tartaglia, G.M. Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study. Int. J. Environ. Res. Public Health 2021, 18, 1488. https://doi.org/10.3390/ijerph18041488

AMA Style

Farronato M, Dolci C, Boccalari E, Izadi S, Salvatierra Rios LH, Festa M, Panetta V, De Vito D, Tartaglia GM. Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study. International Journal of Environmental Research and Public Health. 2021; 18(4):1488. https://doi.org/10.3390/ijerph18041488

Chicago/Turabian Style

Farronato, Marco, Carolina Dolci, Elisa Boccalari, Sara Izadi, Luis H. Salvatierra Rios, Maurizio Festa, Valentina Panetta, Danila De Vito, and Gianluca M. Tartaglia 2021. "Serological Profile of Children and Young Adults with at Least One SARS-CoV-2 Positive Cohabitant: An Observational Study" International Journal of Environmental Research and Public Health 18, no. 4: 1488. https://doi.org/10.3390/ijerph18041488

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