Next Article in Journal
Effect of Virtual Reality Exercises on the Cognitive Status and Dual Motor Task Performance of the Aging Population
Next Article in Special Issue
Loss of Skeletal Muscle Mass and Intracellular Water as Undesired Outcomes of Weight Reduction in Obese Hyperglycemic Women: A Short-Term Longitudinal Study
Previous Article in Journal
Are We Ready to Build Back “Healthier?” An Exploratory Analysis of U.S. State-Level Disaster Recovery Plans
 
 
Article

Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis

1
Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
2
Department of Cardiology, Antwerp University Hospital, 2650 Edegem, Belgium
3
Faculty of Medicine and Health Sciences, Ghent University, 9000 Ghent, Belgium
4
Department of Radiology, Antwerp University Hospital, 2650 Edegem, Belgium
5
Department of Endocrinology, Antwerp University Hospital, 2650 Edegem, Belgium
6
Health Department, Bern University of Applied Sciences, 3008 Bern, Switzerland
7
Faculty of Sport and Rehabilitation Sciences, Vrije Universiteit Brussel, 1050 Elsene, Belgium
*
Author to whom correspondence should be addressed.
Academic Editor: Amy Elizabeth Rothberg
Int. J. Environ. Res. Public Health 2021, 18(15), 8004; https://doi.org/10.3390/ijerph18158004
Received: 10 June 2021 / Revised: 19 July 2021 / Accepted: 23 July 2021 / Published: 28 July 2021
(This article belongs to the Special Issue Overweight and Obesity—Diagnosis and Treatment)
Ectopic fat leads to metabolic health problems. This research aimed to assess the effectiveness of a hypocaloric diet intervention together with an unsupervised exercise training program in comparison with a hypocaloric diet alone to reduce ectopic fat deposition. Sixty-one premenopausal women with overweight or obesity participated in this controlled trial and were each randomised into either a usual care group (hypocaloric diet) or intervention group (hypocaloric diet + unsupervised exercise training). Ectopic fat deposition, metabolic parameters, incremental costs from a societal perspective and incremental quality-adjusted life years (QALYs) were assessed before, during and after the six-month intervention period. In the total sample, there was a significant decrease in visceral adipose tissue (VAT: −18.88 cm2, 95% CI −11.82 to −25.95), subcutaneous abdominal adipose tissue (SAT: −46.74 cm2, 95% CI −29.76 to −63.18), epicardial fat (ECF: −14.50 cm3, 95% CI −10.9 to −18.98) and intrahepatic lipid content (IHL: −3.53%, 95% CI −1.72 to −5.32). Consequently, an “adapted” economic analysis revealed a non-significant decrease in costs and an increase in QALYs after the intervention. No significant differences were found between groups. A multidisciplinary lifestyle approach seems successful in reducing ectopic fat deposition and improving the metabolic risk profile in women with overweight and obesity. The addition of unsupervised exercise training did not further improve the metabolic health or phenotype over the six months. View Full-Text
Keywords: exercise; overweight; body fat distribution; ectopic fat exercise; overweight; body fat distribution; ectopic fat
Show Figures

Figure 1

MDPI and ACS Style

Hens, W.; Vissers, D.; Verhaeghe, N.; Gielen, J.; Van Gaal, L.; Taeymans, J. Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis. Int. J. Environ. Res. Public Health 2021, 18, 8004. https://doi.org/10.3390/ijerph18158004

AMA Style

Hens W, Vissers D, Verhaeghe N, Gielen J, Van Gaal L, Taeymans J. Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis. International Journal of Environmental Research and Public Health. 2021; 18(15):8004. https://doi.org/10.3390/ijerph18158004

Chicago/Turabian Style

Hens, Wendy, Dirk Vissers, Nick Verhaeghe, Jan Gielen, Luc Van Gaal, and Jan Taeymans. 2021. "Unsupervised Exercise Training Was Not Found to Improve the Metabolic Health or Phenotype over a 6-Month Dietary Intervention: A Randomised Controlled Trial with an Embedded Economic Analysis" International Journal of Environmental Research and Public Health 18, no. 15: 8004. https://doi.org/10.3390/ijerph18158004

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop