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Open AccessBrief Report

Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency

1
Health Sciences Research Unit: Nursing (UICISA:E), Nursing School of Coimbra (ESEnfC), 3046-851 Coimbra, Portugal
2
Instituto de Ciências da Saúde, Universidade Católica Portuguesa, 4169-005 Porto, Portugal
3
Biophysics Institute, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of CIMAGO, Faculty of Medicine, CNC.IBILI, Faculty of Medicine, University of Coimbra, Polo das Ciências da Saúde Azinhaga de Santa Comba, 3000-354 Coimbra, Portugal
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(21), 8209; https://doi.org/10.3390/ijerph17218209
Received: 13 October 2020 / Revised: 29 October 2020 / Accepted: 5 November 2020 / Published: 6 November 2020
This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a pre- and post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush. View Full-Text
Keywords: double-chamber syringes; vascular access devices; flushing; patent review double-chamber syringes; vascular access devices; flushing; patent review
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MDPI and ACS Style

Sousa, L.B.; Santos-Costa, P.; Marques, I.A.; Cruz, A.; Salgueiro-Oliveira, A.; Parreira, P. Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency. Int. J. Environ. Res. Public Health 2020, 17, 8209. https://doi.org/10.3390/ijerph17218209

AMA Style

Sousa LB, Santos-Costa P, Marques IA, Cruz A, Salgueiro-Oliveira A, Parreira P. Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency. International Journal of Environmental Research and Public Health. 2020; 17(21):8209. https://doi.org/10.3390/ijerph17218209

Chicago/Turabian Style

Sousa, Liliana B.; Santos-Costa, Paulo; Marques, Inês A.; Cruz, Arménio; Salgueiro-Oliveira, Anabela; Parreira, Pedro. 2020. "Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency" Int. J. Environ. Res. Public Health 17, no. 21: 8209. https://doi.org/10.3390/ijerph17218209

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