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Communication

The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature

1
Postgraduate Medical School in Public Health, University of Florence, 50134 Florence, Italy
2
Department of Health Sciences, University of Florence, 50134 Florence, Italy
3
Netherlands Institute for Health Services Research (Nivel), 3513 Utrecht, The Netherlands
4
Molecular and Lifestyle Epidemiology Branch, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), 50139 Florence, Italy
*
Author to whom correspondence should be addressed.
Int. J. Environ. Res. Public Health 2020, 17(21), 7870; https://doi.org/10.3390/ijerph17217870
Received: 28 September 2020 / Revised: 21 October 2020 / Accepted: 23 October 2020 / Published: 27 October 2020
We reviewed the association between seasonal influenza vaccination and the risk of SARS-CoV-2 infection or complicated illness or poor outcome (e.g., severe disease, need for hospitalization or ventilatory support, or death) among COVID-19 patients. None of the studies that were reviewed (n = 12) found a significant increase in the risk of infection or in the illness severity or lethality, and some reported significantly inverse associations. Our findings support measures aimed at raising influenza vaccination coverage in the coming months. View Full-Text
Keywords: SARS-CoV-2; influenza vaccine; systematic review; infection; severity; risk SARS-CoV-2; influenza vaccine; systematic review; infection; severity; risk
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MDPI and ACS Style

Del Riccio, M.; Lorini, C.; Bonaccorsi, G.; Paget, J.; Caini, S. The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature. Int. J. Environ. Res. Public Health 2020, 17, 7870. https://doi.org/10.3390/ijerph17217870

AMA Style

Del Riccio M, Lorini C, Bonaccorsi G, Paget J, Caini S. The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature. International Journal of Environmental Research and Public Health. 2020; 17(21):7870. https://doi.org/10.3390/ijerph17217870

Chicago/Turabian Style

Del Riccio, Marco, Chiara Lorini, Guglielmo Bonaccorsi, John Paget, and Saverio Caini. 2020. "The Association between Influenza Vaccination and the Risk of SARS-CoV-2 Infection, Severe Illness, and Death: A Systematic Review of the Literature" International Journal of Environmental Research and Public Health 17, no. 21: 7870. https://doi.org/10.3390/ijerph17217870

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