Allergic Anaphylactic Risk in Farming Activities: A Systematic Review
Abstract
:1. Introduction
2. Materials and Methods
2.1. Literature Research
2.2. Quality Assessment
2.3. Eligibility and Inclusion Criteria
2.4. Exclusion Criteria
3. Results
3.1. Reviews
3.2. Original Articles
3.2.1. Main Diseases
3.2.2. Allergens
3.2.3. Agricultural Sectors and Activities
3.2.4. Demographic Characteristics of Involved Workers
3.3. Case Series and Case Report
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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First Author | Year | Study | Key Messages |
---|---|---|---|
Al-Maneea | 2013 | cross-sectional | Exposure to animal products (dust, pigeon, dog, cat, turkey) exacerbates allergic asthma |
Ballal | 2016 | narrative review | Storage mites and cow’s dander are the commonest causes of occupational rhinitis in this occupational group |
Bilò | 2012 | narrative review | Allergic beekeepers represent unique populations for epidemiological, venom allergy immunopathogenesis and mechanism studies |
Bobolea | 2011 | case control | Spiders represent an important but as yet unexplored source of indoor allergens, especially in agricultural environments |
Carballo | 2017 | case-control | High concentrations of HBV-sIgG4 associated with less severe sting reactions in beekeepers. HBV-sIgE tended to be higher in beekeepers with more severe reactions, while total serum IgE was lower in beekeepers than in controls. |
Çelıksoy | 2014 | cross-sectional | The risk of a severe reaction to bee stings increases with the degree of exposure and beekeepers are at the highest risk |
Elholm | 2018 | cohort Studies | Storage mites can be typical occupational allergen for which new sensitization might occur in the first years of a farmer’s work life. |
Ercilla-Montserrat | 2017 | experimental study | It is possible to recirculate the air of the i-RTG to the building, thus to converting the system into an Bi-RTG without posing health risks due to allergies for the building users if the biological air quality is monitored and the corresponding preventive measures are taken, even with the installation of air filters. |
Galli | 2015 | case-control | The prevalence of allergic diseases is lower in people who reside in the countryside and therefore are exposed to bacterial, parasitic, and viral infections during childhood |
Gascon | 2012 | cohort study | During the harvesting season, the prevalence of wheeze and eye problems almost doubled in workers exposed to bagasse and other types of dust |
Green | 2018 | narrative Review | Health and safety precautions used in the landscape industry can be used by gardeners, landscapers and arborists to reduce or eliminate exposure to biological hazards |
Green | 2018 | narrative Review | Occupational fungal exposures include a much broader diversity of fungi than once thought |
Green | 2018 | pilot study | Potential exposure to microbiological hazards, such as Actinobacteria and cannabis fungal, in workers that harvest, bud strip or hand trim organically produced cannabis. |
Guan | 2016 | case-control | The use of sIgE/T-IgE results is a useful diagnostic parameter in determining honeybee venom allergy |
Harun | 2019 | narrative review | Wheat harvesting has implicated in respiratory symptoms, with fungal spores as the predominant aeroallergen |
Jain | 2012 | case report | Venom bee stings can cause neurological complications (stroke, seizure, aphasia, dysarthria, apraxia, ataxia and coma) |
Merget | 2016 | case control | Triticale allergy may occur as a distinct allergy in farmers |
Munstedt | 2010 | cross-sectional | Desensitization can result in a complete absence of symptoms after re-exposure to bee stings |
Ndlovu | 2014 | cross-sectional | Pesticide exposure among women farm workers is associated with increased risk of ocular nasal symptoms and an elevated asthma symptom |
Nordgren | 2018 | narrative Review | Working and/or living near CAFOs (concentrated animal feeding operations) is a risk factor for development of various respiratory diseases due to various contaminants, like biological dust, pesticides and zoonotic pathogens |
Nordgren | 2016 | narrative Review | In agricultural industry, occupational exposures to bioaerosols and inorganic aerosols lead to increased risk for lung disease amongst workers |
Oosterhaven | 2019 | cross-sectional | The prevalence of hand eczema in beekeepers was higher than in the general population, but a small subset of beekeepers suffered it |
Patiwael | 2010 | cohort study | Pollen from bell pepper plants cultivated in greenhouses cause occupational allergic disease |
Patiwael | 2010 | cross-sectional | Allergic symptoms attributable to the workplace are present among a proportion of strawberry greenhouse employees |
Perez-Calderon | 2017 | case-series | Sensitization to no-pollen tree structures, such as peach leaves, may cause occupational respiratory symptoms. |
Perotin | 2015 | cross-sectional | Work-related respiratory symptoms are frequent and associated with a sensitization to gramineae and with activities performed close to vine in late spring |
Pesonen | 2020 | cross-sectional | Main causes of CU and PCD in Finnish workers are animal dander, grain, NRL, and plant- and animal derived foods. |
Quirce | 2011 | narrative review | Asthma rapidly accelerated with the advent of new technologies introducing a spectrum of new agents into the workplace |
Ramavovololona | 2014 | cohort study | Major allergens β-expansins, profilin and polygalacturonase were characterized both in maize and rice pollen |
Reeb-Whitaker | 2014 | case series | Occupational exposure to hop dust is associated with respiratory disease, especially in hop workers |
Rennie | 2015 | cross-sectional | There are associations between atopic sensitization and farm living that appear to vary by sex. Specific allergens appear to be more important for an increase in or protection from allergy that is related to the timing of farming exposures. |
Richter | 2011 | cross-sectional | Factors that predisposed beekeepers to allergic reactions are female gender, having a family member with bee venom allergy, more than 2 years of beekeeping and premedication with an antihistamine |
Sabino | 2012 | case control | This study confirmed the presence and distribution of Aspergillus in Portuguese poultry and swine farms |
Spiewak | 2017 | cross-sectional | Work with hops is the kind of plant production associated with most frequent skin diseases, followed by work with grain, hay and straw. Skin prick tests do not correlate well with referred symptoms. |
Upadhyay | 2019 | narrative review | People involved in spice agriculture and food industries are at greater risk to long and short-term respiratory issues |
Viegas | 2013 | cross-sectional | Poultry farm workers are more prone to suffer from respiratory ailments and this may be attributed to higher concentrations of particulate in the dust |
First Author | Included Subjects | Allergic Disease | Allergens | Category Workers | Scores |
---|---|---|---|---|---|
Ballal SG | Rhinitis | various | Farmers, florists, greenhouse, animal, grain handlers | I.5 | |
Bilò MB | Anaphylaxis | Bee Venom | Beekeepers | I.5 | |
Green BJ | Respiratory disease | Fungal bioaerosols | Various | I.5 | |
Green BJ | Respiratory, dermatologic | Pollen, Arthropods, Bioaerosol | Gardeners, Horticulture, Greenhouse | I.5 | |
Harun DS | Asthma | Pollen | agricultural activities | I.5 | |
Nordgren M | Respiratory disease | Biological Dust, Bioaerosols | Various | I.5 | |
Nordgren M | Respiratory disease | Aeroallergens | Farmers | I.5 | |
Quirce S | Asthma | Various | Various | I.6 | |
Upadhyay E | Respiratory, dermatologic | Arthropods | Spice agricultural workers | I.5 | |
Bobolea I | 1 case, 5 controls | Asthma | Arthropods | Cereal workers | N.6 |
Carballo I | 158 cases, 465 controls | Anaphylaxis | Honeybee Venom | Beekeepers | N.6 |
Elholm G | not specified | Sensitization | Arthropods | Farmer, Millers, Cattlemen | N.7 |
Ercilla-Montserrat M | not specified | Respiratory disease | Biological dust | Greenhouses worker | n.a. |
Galli L | 101 cases, 82 controls | Respiratory disease | Aeroallergens | Swine breeders | N.6 |
Gascon M | N.74 | Respiratory, ocular disease | Biological dust | Sugarcane workers | N.6 |
Green BJ | not specified | Respiratory, dermatologic | Microbiological hazard | Farm Cannabis workers | n.a. |
Guan K | 54 cases | Anaphylaxis | Honeybee Venom | Beekeepers | N.3 |
Jain J | N.1 | Stroke | Bee Venom | Beekeepers | n.a. |
Merget R | 1 case, 4 controls | Asthma | Triticale | Farmers | N.6 |
Patiwael JA | N.322 | Respiratory disease | Pepper Pollen | Greenhouses | N.7 |
Perez-Calderon | N.37 | Respiratory disease | Peach tree | Peach Crop | n.a. |
Ramavovololona | N.65 | Respiratory, dermatologic | Pollen | Maize, Rice Crop | N.5 |
Reeb-Whitaker | N.57 | Respiratory disease | Lupulus | Hop workers | n.a. |
Sabino R | 47 cases, 28 controls | Respiratory, dermatologic | Aspergillus | Swine, Poultry workers | N.7 |
First Author | Included Subjects | Allergic Disease | Allergen | Category Workers | Score |
---|---|---|---|---|---|
Al-Maneea | N.10 | Respiratory disease | Animals | Not specified | N.5 |
Çelıksoy MH | N.301 | Anaphylaxis | Bee Venom | Beekeepers | N.5 |
Munstedt K | N.63 | Anaphylaxis | Bee Venom | Beekeepers | N.5 |
Ndlovu V | N.211 | Asthma | Pesticide | Not specified | N.6 |
Oostarhaven | N.833 | Dermatitis | Various (propolis) | Beekeepers | N.7 |
Patiwael JA | N.75 | Respiratory, dermatologic | Strawberry Pollen | Greenhouses | N.6 |
Perotin JM | N.307 | Respiratory disease | Aeroallergens | Vineyard workers | N.5 |
Pesonen M | N.570 | Dermatitis | Cow, grain, flour dust | farmers, livestock workers, gardeners | N.6 |
Rennie DC | n.11982 | Atopic/allergic reaction | Aeroallergens | Farmers | N.7 |
Richter AG | N.852 | Anaphylaxis | Bee Venom | Beekeepers | N.6 |
Spiewak | N.440 | Dermatitis | Biological dust | students of agriculture | N.8 |
Viegas S | N.46 | Respiratory disease | Poultry dust | Poultry farmworkers | N.5 |
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Arcangeli, G.; Traversini, V.; Tomasini, E.; Baldassarre, A.; Lecca, L.I.; Galea, R.P.; Mucci, N. Allergic Anaphylactic Risk in Farming Activities: A Systematic Review. Int. J. Environ. Res. Public Health 2020, 17, 4921. https://doi.org/10.3390/ijerph17144921
Arcangeli G, Traversini V, Tomasini E, Baldassarre A, Lecca LI, Galea RP, Mucci N. Allergic Anaphylactic Risk in Farming Activities: A Systematic Review. International Journal of Environmental Research and Public Health. 2020; 17(14):4921. https://doi.org/10.3390/ijerph17144921
Chicago/Turabian StyleArcangeli, Giulio, Veronica Traversini, Emanuela Tomasini, Antonio Baldassarre, Luigi Isaia Lecca, Raymond P. Galea, and Nicola Mucci. 2020. "Allergic Anaphylactic Risk in Farming Activities: A Systematic Review" International Journal of Environmental Research and Public Health 17, no. 14: 4921. https://doi.org/10.3390/ijerph17144921