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Mar. Drugs 2011, 9(5), 690-695;

Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus

Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
Liaoning Norm University, Dalian 116029, China
Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China
Key Laboratory of Marine Bio-resources Sustainable Utilization in Liaoning Province’s University, Dalian Fisheries University, Dalian 116023, China
Flinders Centre for Marine Bioprocessing and Bioproducts, School of Medicine, Flinders University, Adelaide, SA 5042, Australia
Authors to whom correspondence should be addressed.
Received: 9 March 2011 / Revised: 3 April 2011 / Accepted: 13 April 2011 / Published: 26 April 2011
(This article belongs to the Special Issue Biomedicines from Marine Symbioses)
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One new nucleoside derivative, named 3-acetyl-5-methyl-2′-deoxyuridine (1), along with two known compounds 3,5-dimethyl-2′-deoxyuridine (2) and 3-methyl-2′-deoxyuridine (3), were isolated from the cultures of Streptomyces microflavus. This strain was an associated actinomycete isolated from the marine sponge Hymeniacidon perlevis collected from the coast of Dalian (China). Their structures were elucidated by detailed NMR and MS spectroscopic analysis as well as comparison with literature data. View Full-Text
Keywords: actinomycete; Streptomyces microflavus; Hymeniacidon perlevis; deoxyuridine actinomycete; Streptomyces microflavus; Hymeniacidon perlevis; deoxyuridine
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Li, K.; Li, Q.-L.; Ji, N.-Y.; Liu, B.; Zhang, W.; Cao, X.-P. Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus. Mar. Drugs 2011, 9, 690-695.

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