Next Article in Journal
Novel Anti-MRSA Peptide from Mangrove-Derived Virgibacillus chiguensis FN33 Supported by Genomics and Molecular Dynamics
Previous Article in Journal
Marine-Derived Compounds Combined with Nanoparticles: A Focus on the Biomedical and Pharmaceutical Sector
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Marine Drugs
Volume 23
Issue 5
10.3390/md23050208
marinedrugs-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Biochemical Composition and Alkaline Extraction Optimization of Soluble Bioactive Compounds from the Green Algae Caulerpa cylindraceae

by
Amani Tahar
1,
Haïfa Zghida
1,
Débora Tomazi Pereira
2,*,
Nathalie Korbee
2,
Helen Treichel
3,
Félix L. Figueroa
2 and
Lotfi Achour
1
1
Higher Institute of Biotechnology of Monastir (ISBM), Research Laboratory ‘Bioressources: Integrative Biology & Valorization’ (BIOLIVAL) LR14ES06, University of Monastir, Av, Taher Haddad B.P. n°74, Monastir 5000, Tunisia
2
Andalusian Institute of Blue Biotechnology and Development (IBYDA), Experimental Center Grice Hutchinson, University of Malaga, Lomas de San Julián, 29004 Malaga, Spain
3
Laboratory of Microbiology and Bioprocess, Federal University of Fronteira Sul, Erechim 99700-970, Brazil
*
Author to whom correspondence should be addressed.
Mar. Drugs 2025, 23(5), 208; https://doi.org/10.3390/md23050208
Submission received: 2 April 2025 / Revised: 5 May 2025 / Accepted: 13 May 2025 / Published: 14 May 2025
(This article belongs to the Special Issue New Methods in Extraction and Isolation of Marine Natural Products)
Browse Figure
Review Reports Versions Notes

Abstract

There is a growing interest in studying the bioactive compounds of invasive green macroalga Caulerpa cylindracea due to their potential biotechnological applications. Algal samples were collected from two sites and seasons. Elemental analysis showed the abundance of carbon in the raw material as a source of carbohydrates. The total protein content in different samples ranged from 8.17 to 9.98%. Total lipids in different samples were around 2%. Fatty acid (FA) results revealed the presence of various types, including omega-3 and omega-6 PUFA. Furthermore, an alkaline hydrolysis optimization using response surface methodology was investigated to extract soluble compounds. It showed that the best combination for polyphenols and ABTS was 12.5% sodium carbonate (SC) at 100 °C for 8 h; however, the best combination for proteins and carbohydrates was 7.5% SC at 100 °C for 5 h. A combination of ultrasound pretreatments was carried out to assess the enhancement of the contents. Thus, an increasing amount was recorded for polyphenols and antioxidant capacity. Ultrasound pretreatment results in decreasing extraction time for all compounds. Results showed that the invasive seaweeds, causing environmental impacts in the Mediterranean Sea, represent an interesting source of bioactive compounds.
Keywords: alkaline hydrolysis; bioactive compounds; Caulerpa cylindracea; fatty acid; ultrasound-assisted extraction alkaline hydrolysis; bioactive compounds; Caulerpa cylindracea; fatty acid; ultrasound-assisted extraction
Graphical Abstract

Share and Cite

MDPI and ACS Style

Tahar, A.; Zghida, H.; Pereira, D.T.; Korbee, N.; Treichel, H.; Figueroa, F.L.; Achour, L. Biochemical Composition and Alkaline Extraction Optimization of Soluble Bioactive Compounds from the Green Algae Caulerpa cylindraceae. Mar. Drugs 2025, 23, 208. https://doi.org/10.3390/md23050208

AMA Style

Tahar A, Zghida H, Pereira DT, Korbee N, Treichel H, Figueroa FL, Achour L. Biochemical Composition and Alkaline Extraction Optimization of Soluble Bioactive Compounds from the Green Algae Caulerpa cylindraceae. Marine Drugs. 2025; 23(5):208. https://doi.org/10.3390/md23050208

Chicago/Turabian Style

Tahar, Amani, Haïfa Zghida, Débora Tomazi Pereira, Nathalie Korbee, Helen Treichel, Félix L. Figueroa, and Lotfi Achour. 2025. "Biochemical Composition and Alkaline Extraction Optimization of Soluble Bioactive Compounds from the Green Algae Caulerpa cylindraceae" Marine Drugs 23, no. 5: 208. https://doi.org/10.3390/md23050208

APA Style

Tahar, A., Zghida, H., Pereira, D. T., Korbee, N., Treichel, H., Figueroa, F. L., & Achour, L. (2025). Biochemical Composition and Alkaline Extraction Optimization of Soluble Bioactive Compounds from the Green Algae Caulerpa cylindraceae. Marine Drugs, 23(5), 208. https://doi.org/10.3390/md23050208

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop