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Open AccessCommunication

Bromophenolics from the Red Alga Polysiphonia decipiens

1
School of Science (Applied Chemistry and Environmental Science), RMIT University, GPO Box 2476V Melbourne, VIC 3001, Australia
2
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia
*
Author to whom correspondence should be addressed.
Mar. Drugs 2019, 17(9), 497; https://doi.org/10.3390/md17090497
Received: 25 July 2019 / Revised: 15 August 2019 / Accepted: 22 August 2019 / Published: 26 August 2019
The isolation and the structure determination of a new bromophenolic compound, polysiphonol (10), as well as five previously reported compounds, (48), from the red alga Polysiphonia decipiens is reported. In addition, the absolute configuration of the natural product rhodomelol (8) could be unequivocally confirmed for the first time, and on biosynthetic grounds, the absolute configuration of polysiphonol (10) was tentatively suggested. Compounds 48 were evaluated for their antibacterial activity against both Gram-positive and Gram-negative bacteria, but none of the compounds showed any appreciable activity. View Full-Text
Keywords: Polysiphonia decipiens; bromophenolics; marine natural products; structural elucidation Polysiphonia decipiens; bromophenolics; marine natural products; structural elucidation
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MDPI and ACS Style

Lever, J.; Curtis, G.; Brkljača, R.; Urban, S. Bromophenolics from the Red Alga Polysiphonia decipiens. Mar. Drugs 2019, 17, 497.

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