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Mar. Drugs 2018, 16(9), 292; https://doi.org/10.3390/md16090292

Bioactive Prenyl- and Terpenyl-Quinones/Hydroquinones of Marine Origin

Department of Pharmaceutical Sciences, Pharmaceutical Chemistry Section, CIETUS/IBSAL, Faculty of Pharmacy, University of Salamanca, E-37007 Salamanca, Spain
Dedicated to Prof. Dr. José M. Miguel del Corral on the occasion of his 68th Birthday.
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Received: 22 July 2018 / Revised: 15 August 2018 / Accepted: 17 August 2018 / Published: 21 August 2018
(This article belongs to the Special Issue Progress on Marine Natural Products as Lead Compounds)

Abstract

The sea is a rich source of biological active compounds, among which terpenyl-quinones/hydroquinones constitute a family of secondary metabolites with diverse pharmacological properties. The chemical diversity and bioactivity of those isolated from marine organisms in the last 10 years are summarized in this review. Aspects related to synthetic approaches towards the preparation of improved bioactive analogues from inactive terpenoids are also outlined. View Full-Text
Keywords: meroterpenoids; mixed metabolites; terpenylquinones; terpenylhydroquinones; bioactivity meroterpenoids; mixed metabolites; terpenylquinones; terpenylhydroquinones; bioactivity
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García, P.A.; Hernández, Á.P.; San Feliciano, A.; Castro, M.Á. Bioactive Prenyl- and Terpenyl-Quinones/Hydroquinones of Marine Origin . Mar. Drugs 2018, 16, 292.

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