Next Article in Journal
Pharmacophore-Based Virtual Screening of Novel Inhibitors and Docking Analysis for CYP51A from Penicillium italicum
Previous Article in Journal
Optimization of Bromelain-Aided Production of Angiotensin I-Converting Enzyme Inhibitory Hydrolysates from Stone Fish Using Response Surface Methodology
Previous Article in Special Issue
Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy
Open AccessArticle

Fluorescent Property of Chitosan Oligomer and Its Application as a Metal Ion Sensor

Department of Advanced Organic Materials and Textile System Engineering, Chungnam National University, Daejeon 34134, Korea
Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD 20892, USA
Authors to whom correspondence should be addressed.
Academic Editors: David Harding and Hitoshi Sashiwa
Mar. Drugs 2017, 15(4), 105;
Received: 26 December 2016 / Revised: 13 March 2017 / Accepted: 29 March 2017 / Published: 4 April 2017
(This article belongs to the Special Issue Advances in Marine Chitin and Chitosan II, 2017)
PDF [6566 KB, uploaded 4 April 2017]


An aqueous solution was successfully prepared using a low-molecular-weight chitosan oligomer and FITC, and its structural and fluorescent properties were observed by using 1H NMR, 13C NMR, FT-IR, XRD, UV-Vis, and PL spectrometry. Its application as a metal ion sensor was also evaluated. The fluorescence in the water-soluble chitosan oligomer was a result of the carbamato anion (NHCOO-), and a synthesized FITC-labeled chitosan oligomer exhibited an effective detection effect for copper ion as well as energy transfer by the ion near FITC that caused a fluorescence decrease (quenching). The chitosan oligomer was confirmed to be applicable as a selective and sensitive colorimetric sensor to detect Cu2+. View Full-Text
Keywords: chitosan oligomer; fluorescent property; metal ion sensor chitosan oligomer; fluorescent property; metal ion sensor

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
Printed Edition Available!
A printed edition of this Special Issue is available here.

Share & Cite This Article

MDPI and ACS Style

Lee, H.M.; Kim, M.H.; Yoon, Y.I.; Park, W.H. Fluorescent Property of Chitosan Oligomer and Its Application as a Metal Ion Sensor. Mar. Drugs 2017, 15, 105.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top