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Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms

School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Author to whom correspondence should be addressed.
Academic Editor: Paul Long
Mar. Drugs 2017, 15(3), 68;
Received: 13 December 2016 / Revised: 3 March 2017 / Accepted: 3 March 2017 / Published: 10 March 2017
(This article belongs to the Special Issue Bioactive Compounds from Marine Microbes - II)
PDF [3401 KB, uploaded 10 March 2017]


A growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatics, lactones, steroids, and miscellaneous compounds. View Full-Text
Keywords: marine microbe; sponge-derived microbe; natural product; cytotoxic compound marine microbe; sponge-derived microbe; natural product; cytotoxic compound

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Zhang, H.; Zhao, Z.; Wang, H. Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms. Mar. Drugs 2017, 15, 68.

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