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Mar. Drugs 2014, 12(9), 4898-4911;

Anticancer Effects of Different Seaweeds on Human Colon and Breast Cancers

Department of Biological Science, College of Natural Science, Wonkwang University, Iksan, Jeonbuk 570-749, Korea
Institute for Glycoscience, Wonkwang University, Iksan, Jeonbuk 570-749, Korea
Department of Food Science and Nutrition, Keimyung University, Daegu 704-701, Korea
Department of Parasitology and Tropical Medicine, Kyungpook National University, Daegu 700-422, Korea
Department of Civil and Environmental Engineering, Kookmin University, Seoul 136-702, Korea
Department of Medicine, College of Medicine, Chung-Ang University, Seoul 156-756, Korea
College of Pharmacy, Yonsei University, Veritas D, Yonsei International Campus, Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Received: 17 June 2014 / Revised: 2 September 2014 / Accepted: 9 September 2014 / Published: 24 September 2014
(This article belongs to the Collection Marine Compounds and Cancer)
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Seafoods and seaweeds represent some of the most important reservoirs of new therapeutic compounds for humans. Seaweed has been shown to have several biological activities, including anticancer activity. This review focuses on colorectal and breast cancers, which are major causes of cancer-related mortality in men and women. It also describes various compounds extracted from a range of seaweeds that have been shown to eradicate or slow the progression of cancer. Fucoidan extracted from the brown algae Fucus spp. has shown activity against both colorectal and breast cancers. Furthermore, we review the mechanisms through which these compounds can induce apoptosis in vitro and in vivo. By considering the ability of compounds present in seaweeds to act against colorectal and breast cancers, this review highlights the potential use of seaweeds as anticancer agents. View Full-Text
Keywords: breast cancer; colorectal cancer; seaweed; therapeutic compounds breast cancer; colorectal cancer; seaweed; therapeutic compounds

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Moussavou, G.; Kwak, D.H.; Obiang-Obonou, B.W.; Maranguy, C.A.O.; Dinzouna-Boutamba, S.-D.; Lee, D.H.; Pissibanganga, O.G.M.; Ko, K.; Seo, J.I.; Choo, Y.K. Anticancer Effects of Different Seaweeds on Human Colon and Breast Cancers. Mar. Drugs 2014, 12, 4898-4911.

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