Mar. Drugs 2014, 12(9), 4810-4832; https://doi.org/10.3390/md12094810
Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects
Division of Applied Life Science (BK21 Plus), PMBBRC, Gyeongsang National University, Jinju 660-701, Korea
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Received: 14 June 2014 / Revised: 29 August 2014 / Accepted: 1 September 2014 / Published: 17 September 2014
(This article belongs to the Special Issue Marine Carotenoids (Special Issue))
Abstract
Carotenoids are a class of diverse pigments with important biological roles such as light capture and antioxidative activities. Many novel carotenoids have been isolated from marine organisms to date and have shown various utilizations as nutraceuticals and pharmaceuticals. In this review, we summarize the pathways and enzymes of carotenoid synthesis and discuss various modifications of marine carotenoids. The advances in metabolic engineering and synthetic biology for carotenoid production are also reviewed, in hopes that this review will promote the exploration of marine carotenoid for their utilizations. View Full-TextKeywords:
marine carotenoids; carotenoid synthesis; carotenoid modification; metabolic engineering; synthetic biology; protein engineering
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Wang, C.; Kim, J.-H.; Kim, S.-W. Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects. Mar. Drugs 2014, 12, 4810-4832.
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