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Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives

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Centre for Marine Bioproducts Development, Flinders University, Adelaide, SA 5042, Australia
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Department of Medical Biotechnology, School of Medicine, Flinders University, Adelaide, SA 5042, Australia
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Department of Fisheries Technology, Faculty of Fisheries, Hajee Mohammad Danesh Science and Technology University, Dinajpur 5200, Bangladesh
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Authors to whom correspondence should be addressed.
Mar. Drugs 2014, 12(8), 4539-4577; https://doi.org/10.3390/md12084539
Received: 31 March 2014 / Revised: 7 July 2014 / Accepted: 15 July 2014 / Published: 19 August 2014
(This article belongs to the Special Issue Advances and New Perspectives in Marine Biotechnology)
Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological activity of sponge-derived new natural products discovered between 2001 and 2010. The data has been analyzed with a view to gaining an outlook on the future trends and opportunities in the search for new compounds and their sources from marine sponges. View Full-Text
Keywords: marine sponges; porifera; marine natural products; anticancer; sponge-associated bacteria; drug; bioactive compounds marine sponges; porifera; marine natural products; anticancer; sponge-associated bacteria; drug; bioactive compounds
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Mehbub, M.F.; Lei, J.; Franco, C.; Zhang, W. Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives. Mar. Drugs 2014, 12, 4539-4577.

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