Next Article in Journal
Paralytic Toxins Accumulation and Tissue Expression of α-Amylase and Lipase Genes in the Pacific Oyster Crassostrea gigas Fed with the Neurotoxic Dinoflagellate Alexandrium catenella
Next Article in Special Issue
A Sulfated-Polysaccharide Fraction from Seaweed Gracilaria birdiae Prevents Naproxen-Induced Gastrointestinal Damage in Rats
Previous Article in Journal
Subereamolline A as a Potent Breast Cancer Migration, Invasion and Proliferation Inhibitor and Bioactive Dibrominated Alkaloids from the Red Sea Sponge Pseudoceratina arabica
Open AccessArticle

Further Investigation of the Mediterranean Sponge Axinella polypoides: Isolation of a New Cyclonucleoside and a New Betaine

1
The NeaNat Group, Department of Chemistry of Natural Products, University of Naples “Federico II”, Via D. Montesano 49, Napoli 80131, Italy
2
C.S.I.A.S. (Interdepartmental Center of Instrumental Analysis), University of Naples “Federico II”, Via D. Montesano 49, Napoli 80131, Italy
*
Author to whom correspondence should be addressed.
Deceased on 7 July 2012.
Mar. Drugs 2012, 10(11), 2509-2518; https://doi.org/10.3390/md10112509
Received: 12 September 2012 / Revised: 26 October 2012 / Accepted: 30 October 2012 / Published: 9 November 2012
(This article belongs to the Special Issue Marine Secondary Metabolites)
An exhaustive exploration into the metabolic content of the Mediterranean sponge Axinella-polypoides resulted in the isolation of the new betaine 5 and the new cyclonucleoside 8. The structures of the new metabolites were elucidated by spectroscopic methods assisted by computational methods. The analysis also provided evidence that the sponge does not elaborate pyrrole-imidazole alkaloids (PIAs) but, interestingly, it was shown to contain two already known cyclodipeptides, compounds 9 (verpacamide A) and 10. View Full-Text
Keywords: natural products; sponges; Axinellidae; pyrrole-imidazole alkaloids; taxon-specificity natural products; sponges; Axinellidae; pyrrole-imidazole alkaloids; taxon-specificity
Show Figures

Figure 1

MDPI and ACS Style

Menna, M.; Aiello, A.; D'Aniello, F.; Fattorusso, E.; Imperatore, C.; Luciano, P.; Vitalone, R. Further Investigation of the Mediterranean Sponge Axinella polypoides: Isolation of a New Cyclonucleoside and a New Betaine. Mar. Drugs 2012, 10, 2509-2518.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop