Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. CT Protocol
2.3. Qualitative Image Analysis
2.4. Data Collection
2.5. Statistical Analysis
3. Results
Demographics
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
References
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Characteristic | Total (n = 174) |
---|---|
Age | 64.1 ± 15.8 |
Sex | |
Male | 112 (64.4) |
Female | 62 (35.6) |
Underlying disease | |
None | 28 (16.1) |
Diabetes mellitus | 96 (55.2) |
Hypertension | 94 (54) |
End-stage renal disease | 21 (12.1) |
Dyslipidemia | 19 (10.9) |
Cerebrovascular accident | 15 (8.6) |
Malignancy | 14 (8) |
Liver cirrhosis | 11 (6.3) |
Heart failure | 9 (5.2) |
Chronic obstructive pulmonary disease | 5 (2.9) |
Multiple comorbidities (≥2 diseases) | 87 (50) |
History of trauma associated with cellulitis | 72 (41.4) |
Total | Group I | Group II | p Value | |
---|---|---|---|---|
WBC (103/μL) | 11.1 ± 5.4 | 11.4 ± 5.6 | 10.1 ± 4.7 | 0.172 |
CRP (mg/L) | 11.5 ± 9.6 | 12.2 ± 9.6 | 9.4 ± 9.1 | 0.107 |
ESR (mm/h) | 77.5 ± 37.4 | 76.7 ± 37.6 | 80.3 ± 36.9 | 0.591 |
CT Findings | Total (n = 174) | Group I (n = 130) | Group II (n = 44) | p Value |
---|---|---|---|---|
Skin thickening | 83.9 [78.2–89.1] | 93.1 [88.5–96.9] | 56.8 [43.2–70.5] | <0.001 |
Subcutaneous edema | 94.8 [91.4–97.7] | 97.7 [94.6–100] | 86.4 [75.0–95.5] | <0.001 |
Venous early return on MIP | 82.8 [77.0–87.9] | 86.9 [80.8–92.3] | 70.5 [56.8–84.1] | 0.012 |
Lymph node pathologic finding | 72.4 [65.5–78.7] | 72.3 [64.6–80.0] | 72.7 [59.1–86.4] | 0.957 |
Lymph node enhancement | 79.3 [72.9–85.0] | 80.0 [73.1–86.9] | 77.3 [63.6–88.6] | 0.699 |
Arteriosclerosis obliterans | 25 (14.4) | 12 (9.2) | 13 (29.5) | <0.001 |
CT Features 1 | CT Features 2 | p Value |
---|---|---|
Skin thickening | Subcutaneous edema | <0.001 |
Skin thickening | Venous early return on MIP | 0.011 |
Skin thickening | Lymph node pathology | 0.165 |
Skin thickening | Lymph node enhancement | 0.611 |
Subcutaneous edema | Venous early return on MIP | 0.187 |
Subcutaneous edema | Lymph node pathology | 0.263 |
Subcutaneous edema | Lymph node enhancement | 0.395 |
Venous early return on MIP | Lymph node pathology | 0.001 |
Venous early return on MIP | Lymph node enhancement | 0.011 |
Lymph node pathology | Lymph node enhancement | <0.001 |
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Share and Cite
Nam, I.-C.; Kim, D.-R.; Lee, J.-S.; Kim, J.; Shin, Y.-H.; Won, J.-H.; Lee, Y.-J. Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling. Medicina 2025, 61, 982. https://doi.org/10.3390/medicina61060982
Nam I-C, Kim D-R, Lee J-S, Kim J, Shin Y-H, Won J-H, Lee Y-J. Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling. Medicina. 2025; 61(6):982. https://doi.org/10.3390/medicina61060982
Chicago/Turabian StyleNam, In-Chul, Doo-Ri Kim, Jeong-Sub Lee, Jeongjae Kim, Young-Heun Shin, Jung-Ho Won, and Yong-June Lee. 2025. "Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling" Medicina 61, no. 6: 982. https://doi.org/10.3390/medicina61060982
APA StyleNam, I.-C., Kim, D.-R., Lee, J.-S., Kim, J., Shin, Y.-H., Won, J.-H., & Lee, Y.-J. (2025). Computed Tomography Imaging Characteristics in the Diagnosis and Assessment of Cellulitis in Patients with Leg Swelling. Medicina, 61(6), 982. https://doi.org/10.3390/medicina61060982