Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Protocol
2.2. Inclusion Criteria
- Patients who underwent hemiarthroplasty for a hip fracture, either primarily after trauma or for the management of femoral neck fracture nonunion.
- Patients diagnosed with postoperative hematoma or postoperative prosthetic joint infection.
2.3. Exclusion Criteria
- Patients with bacterial culture results indicating non-staphylococcal colonization.
- Patients who had negative bacterial culture results.
2.4. Statistical Analysis
3. Results
3.1. Patients
3.2. Clinical Outcomes
3.3. DAIR Surgery Outcomes (Twenty-Nine Cases)
3.4. Primary Implant Removal Surgery Outcomes (6 Cases)
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Early Infection (Presented Within 3 Months After HA Surgery) (n = 26) | Late Infection (Presented After 3 Months Post-HA Surgery) (n = 10) | Total Cases (36) | |
---|---|---|---|
Time of presentation (mean, range) weeks | 3.45 weeks (1–10) | 53.4 weeks (15.7–217.3) | 17.7 weeks (1–217.3) |
Age | 79 (52.6–98.8) | 69.7 (53.5–100) | 76.5 years (52.6–100) |
BMI | 27 (16.2–39) | 27 (16–40.4) | 27 (range, 16–40.4) |
Causative organism | MRSA (11) Staphylococcus aureus (6) Coagulase-negative staphylococci (2) Staphylococcus hemolyticus (1) Staphylococcus epidermidis (1) Other staphylococci (5) | MRSA (4) Staphylococcus aureus (2) Other staphylococci (4) | MRSA (15) Non-MRSA (8) Other staphylococci (13) |
Outcome |
|
|
|
Successful DAIR | 8/24 (33.3%) | 1/5 (20%) |
Successful DAIR | Unsuccessful DAIR | |
---|---|---|
Number | 9 (31%) | 20 (69%) |
Age | 78.8 (59.7–100) | 76.3 (52.6–98.9) |
Time from HA till presentation | 1 late acute hematogenous (11.1%), 8 early (88.9%) | 4 late (20%), 16 early (80%) |
Time from presentation till DAIR surgery | 3.4 days ± 2.1 (range, 1–8 days) | 10.6 days ± 13.7 (range, 1–62) |
p = 0.03 (Welch t-test) (statistically significant) | ||
Type of implant | Cemented 8 Uncemented 1 | Cemented 14 Uncemented 6 |
Number of DAIR trials | 1 (6 cases) 2 (3 cases) | 1 (5 cases) 2 (11 cases) 3 (4 cases) |
Outcome | The mean infection-free follow-up was 44.6 months |
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Causative organism |
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© 2025 by the authors. Published by MDPI on behalf of the Lithuanian University of Health Sciences. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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Mahmoud, A.N.; Brule, N.R.; Suk, M.; Horwitz, D.S. Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study. Medicina 2025, 61, 602. https://doi.org/10.3390/medicina61040602
Mahmoud AN, Brule NR, Suk M, Horwitz DS. Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study. Medicina. 2025; 61(4):602. https://doi.org/10.3390/medicina61040602
Chicago/Turabian StyleMahmoud, Ahmed Nageeb, Nicholas R. Brule, Michael Suk, and Daniel Scott Horwitz. 2025. "Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study" Medicina 61, no. 4: 602. https://doi.org/10.3390/medicina61040602
APA StyleMahmoud, A. N., Brule, N. R., Suk, M., & Horwitz, D. S. (2025). Outcomes of Staphylococcal Prosthetic Joint Infection After Hip Hemiarthroplasty: Single Center Retrospective Study. Medicina, 61(4), 602. https://doi.org/10.3390/medicina61040602