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Reply

Reply to Saleh, C. Comment on “Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512”

by
Danira Bažadona
1,
Martina Matovinović
2,
Magdalena Krbot Skorić
1,
Hrvoje Grbavac
3,
Andrej Belančić
4,5 and
Branko Malojčić
1,*
1
Department of Neurology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia
2
Croatian Referral Center for Obesity Treatment, Department of Endocrinology, University Hospital Centre Zagreb, 10000 Zagreb, Croatia
3
University Psychiatric Hospital Vrapce, 10090 Zagreb, Croatia
4
Department of Clinical Pharmacology, Clinical Hospital Centre Rijeka, 51000 Rijeka, Croatia
5
Department of Basic and Clinical Pharmacology with Toxicology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia
*
Author to whom correspondence should be addressed.
Medicina 2024, 60(7), 1158; https://doi.org/10.3390/medicina60071158
Submission received: 28 May 2024 / Accepted: 15 July 2024 / Published: 18 July 2024
Versions Notes
We would like to begin by expressing our gratitude for the interest shown in our research [1,2].
We agree that a composite carotid intima–media thickness (CIMT) measurement that includes the common carotid artery (CCA), the carotid bifurcation and internal carotid artery (ICA) could provide more accurate measurement, but this type of measurement was not conducted for several reasons. First, as already mentioned, there is no universally accepted standardized measurement protocol and most studies were performed using only CCA IMT [3]. CCA IMT is a well-known marker of atherosclerosis and its association with cardiovascular and cerebrovascular events has been proven repeatedly [4,5,6]. The measurement of CCA IMT is easier to obtain and is highly reliable with less variability in measurements [6,7].
To conclude, although we agree our study protocol has its limitations, we believe that it provided more feasible patient examination and more comparable results.

Conflicts of Interest

The authors declare no conflict of interest.

References

  1. Bažadona, D.; Matovinović, M.; Krbot Skorić, M.; Grbavac, H.; Belančić, A.; Malojčić, B. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512. [Google Scholar] [CrossRef] [PubMed]
  2. Saleh, C. Comment on Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512. Medicina 2024, 60, 981. [Google Scholar] [CrossRef]
  3. Ling, Y.; Wan, Y.; Barinas-Mitchell, E.; Fujiyoshi, A.; Cui, H.; Maimaiti, A.; Xu, R.; Li, J.; Suo, C.; Zaid, M. Varying Definitions of Carotid Intima-Media Thickness and Future Cardiovascular Disease: A Systematic Review and Meta-Analysis. J. Am. Heart Assoc. 2023, 12, e031217. [Google Scholar] [CrossRef] [PubMed]
  4. Simons, P.C.; Algra, A.; Bots, M.L.; Grobbee, D.E.; van der Graaf, Y. Common carotid intima-media thickness and arterial stiffness: Indicators of cardiovascular risk in high-risk patients the SMART study (Second Manifestations of ARTerial Disease). Circulation 1999, 100, 951–957. [Google Scholar] [CrossRef] [PubMed]
  5. Bots, M.L.; Hoes, A.W.; Koudstaal, P.J.; Hofman, A.; Grobbee, D.E. Common carotid intima-media thickness and risk of stroke and myocardial infarction: The Rotterdam Study. Circulation 1997, 96, 1432–1437. [Google Scholar] [CrossRef] [PubMed]
  6. Frauchiger, B.; Schmid, H.P.; Roedel, C.; Moosmann, P.; Staub, D. Comparison of carotid arterial resistive indices with intima-media thickness as sonographic markers of atherosclerosis. Stroke 2001, 32, 836–841. [Google Scholar] [CrossRef] [PubMed]
  7. O’Leary, D.H.; Polak, J.F.; Wolfson, S.K., Jr.; Bond, M.G.; Bommer, W.; Sheth, S.; Psaty, B.M.; Sharrett, A.R.; Manolio, T.A. Use of sonography to evaluate carotid atherosclerosis in the elderly: The cardiovascular health study. Stroke 1991, 22, 1155–1163. [Google Scholar] [CrossRef] [PubMed]
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MDPI and ACS Style

Bažadona, D.; Matovinović, M.; Krbot Skorić, M.; Grbavac, H.; Belančić, A.; Malojčić, B. Reply to Saleh, C. Comment on “Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512”. Medicina 2024, 60, 1158. https://doi.org/10.3390/medicina60071158

AMA Style

Bažadona D, Matovinović M, Krbot Skorić M, Grbavac H, Belančić A, Malojčić B. Reply to Saleh, C. Comment on “Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512”. Medicina. 2024; 60(7):1158. https://doi.org/10.3390/medicina60071158

Chicago/Turabian Style

Bažadona, Danira, Martina Matovinović, Magdalena Krbot Skorić, Hrvoje Grbavac, Andrej Belančić, and Branko Malojčić. 2024. "Reply to Saleh, C. Comment on “Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512”" Medicina 60, no. 7: 1158. https://doi.org/10.3390/medicina60071158

APA Style

Bažadona, D., Matovinović, M., Krbot Skorić, M., Grbavac, H., Belančić, A., & Malojčić, B. (2024). Reply to Saleh, C. Comment on “Bažadona et al. The Interconnection between Carotid Intima–Media Thickness and Obesity: Anthropometric, Clinical and Biochemical Correlations. Medicina 2023, 59, 1512”. Medicina, 60(7), 1158. https://doi.org/10.3390/medicina60071158

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