Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults
Abstract
:1. Introduction
2. Materials and Methods
- Eating habits;
- Blood chemistry tests (fasting glycaemia, lipid picture (total cholesterol and HDL cholesterol), and liver enzymes (AST and ALT transaminases));
- Anthropometric parameters (body weight, height, BMI calculation, and waist circumference);
- Nutrition status (bioimpedance test, FM (fat mass), and FFM (lean mass));
- Liver ultrasound;
- Oxidative stress;
- Adherence to the Mediterranean diet.
- (1)
- Carbohydrates should be 45–60% of TCI (simple carbohydrates < 10% of TCI);
- (2)
- Lipids should be 20–35% of TCI (2–4 g/day of omega-3);
- (3)
- Proteins should be 20–25% of TCI.
- (a)
- Recording reminder of the foods eaten during meals in a day by means of a quantitative assessment;
- (b)
- Registering remembrance of foods consumed habitually and recently through quantitative assessment and registering frequency of consumption.
3. Statistical Analysis
4. Results
5. Discussion
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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T0 | T1 | ||
---|---|---|---|
Variables | Mean ± SD | Mean ± SD | p-Student |
Age | 43.0 ± 12.40 | - | - |
Education | 14.19 ± 3.42 | - | - |
MoCA | 27.2 ± 1.23 | 27.41 ± 1.37 | 0.13 |
Total Cholesterol | 267.14 ± 12.87 | 190.55 ± 121.43 | <0.001 *± |
HDL | 33.00 ± 3.18 | 42.27 ± 4.42 | <0.001 * |
Triglycerides | 217.64 ± 9.04 | 90.86 ± 4.99 | <0.001 *± |
Glycaemia | 137.68 ± 8.92 | 92.45 ± 4.30 | <0.001 * |
AST | 48.82 ± 2.82 | 28.32 ± 3.05 | <0.001 * |
ALT | 88.91 ± 3.89 | 31.32 ± 2.82 | <0.001 * |
BMI | 37.36 ± 2.57 | 31.23 ± 2.35 | <0.001 * |
Circumference | 118.55 ± 2.56 | 101.45 ± 2.97 | <0.001 *± |
FM | 35.05 ± 3.46 | 29.27 ± 2.71 | <0.001 * |
FFM | 64.95 ± 3.46 | 70.73 ± 2.71 | <0.001 * |
MDA | 0.98 ± 0.15 | 0.36 ± 0.07 | <0.001 * |
GSH | 5.90 ± 0.55 | 12.89 ± 1.37 | <0.001 * |
MAI | 1.92 ± 0.14 | 4.34 ± 0.46 | <0.001 *± |
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Metro, D.; Buda, M.; Manasseri, L.; Corallo, F.; Cardile, D.; Lo Buono, V.; Quartarone, A.; Bonanno, L. Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults. Medicina 2023, 59, 638. https://doi.org/10.3390/medicina59030638
Metro D, Buda M, Manasseri L, Corallo F, Cardile D, Lo Buono V, Quartarone A, Bonanno L. Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults. Medicina. 2023; 59(3):638. https://doi.org/10.3390/medicina59030638
Chicago/Turabian StyleMetro, Daniela, Martina Buda, Luigi Manasseri, Francesco Corallo, Davide Cardile, Viviana Lo Buono, Angelo Quartarone, and Lilla Bonanno. 2023. "Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults" Medicina 59, no. 3: 638. https://doi.org/10.3390/medicina59030638