Next Article in Journal
Calcium Channel Blockers as Tocolytics: Principles of Their Actions, Adverse Effects and Therapeutic Combinations
Next Article in Special Issue
Loss of Response to Long-Term Infliximab Therapy in Children with Crohn’s Disease
Previous Article in Journal
FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver
Previous Article in Special Issue
Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

Evolution of Biologics Screening Technologies

MedImmune Ltd, Milstein Building, Granta Park, Cambridge CB21 6GH, UK
Author to whom correspondence should be addressed.
Pharmaceuticals 2013, 6(5), 681-688;
Received: 5 February 2013 / Revised: 23 April 2013 / Accepted: 8 May 2013 / Published: 14 May 2013
(This article belongs to the Special Issue Biologics)
Screening for biologics, in particular antibody drugs, has evolved significantly over the last 20 years. Initially, the screening processes and technologies from many years experience with small molecules were adopted and modified to suit the needs of biologics discovery. Since then, antibody drug discovery has matured significantly and is today investing earlier in new technologies that commercial suppliers are now developing specifically to meet the growing needs of large molecule screening. Here, we review the evolution of screening and automation technologies employed in antibody discovery and highlight the benefits that these changes have brought. View Full-Text
Keywords: high throughput screening; assay technologies; therapeutic antibodies high throughput screening; assay technologies; therapeutic antibodies
Show Figures

Graphical abstract

MDPI and ACS Style

Cariuk, P.; Gardener, M.J.; Vaughan, T.J. Evolution of Biologics Screening Technologies. Pharmaceuticals 2013, 6, 681-688.

AMA Style

Cariuk P, Gardener MJ, Vaughan TJ. Evolution of Biologics Screening Technologies. Pharmaceuticals. 2013; 6(5):681-688.

Chicago/Turabian Style

Cariuk, Peter, Matthew J. Gardener, and Tristan J. Vaughan 2013. "Evolution of Biologics Screening Technologies" Pharmaceuticals 6, no. 5: 681-688.

Find Other Styles

Article Access Map by Country/Region

Only visits after 24 November 2015 are recorded.
Back to TopTop