Next Article in Journal
The Effects of Echinacea (EP107TM) on Anxiety: A Comparison of Anxiety Measures in a Randomized, Double Blind, Placebo-Controlled Study
Previous Article in Journal
Drug Treatment Direction Based on the Molecular Mechanism of Breast Cancer Brain Metastasis
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Pharmaceuticals
Volume 18
Issue 2
10.3390/ph18020263
pharmaceuticals-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Retraction of Pharmaceuticals 2022, 15(7), 795.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Retraction

RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795

by
Jhen-Yu Huang
1,
You-Cian Lin
2,3,
Han-Min Chen
4,
Jiun-Tsai Lin
5 and
Shao-Hsuan Kao
1,6,*
1
Institute of Medicine, College of Medicine, Chung Shan Medical University, Taichung City 402306, Taiwan
2
Cardiovascular Division, Surgical Department, China Medical University Hospital, Taichung City 404332, Taiwan
3
School of Medicine, College of Medicine, China Medical University, Taichung City 404332, Taiwan
4
Institute of Applied Science and Engineering, Catholic Fu Jen University, New Taipei 242048, Taiwan
5
Energenesis Biomedical Co., Ltd., Taipei 114694, Taiwan
6
Department of Medical Research, Chung Shan Medical University Hospital, Taichung City 402306, Taiwan
*
Author to whom correspondence should be addressed.
Pharmaceuticals 2025, 18(2), 263; https://doi.org/10.3390/ph18020263
Submission received: 18 June 2024 / Accepted: 4 February 2025 / Published: 17 February 2025
Versions Notes
The Pharmaceuticals Editorial Office retracts the article “Adenine Combined with Cisplatin Promotes Anticancer Activity against Hepatocellular Cancer Cells through AMPK-Mediated p53/p21 and p38 MAPK Cascades [1]” cited above.
Following publication, concerns were brought to the attention of the Publisher regarding the overlap of an image with another publication representing different experimental conditions.
Adhering to our complaint procedure, an investigation was conducted by the Editorial Office and Editorial Board that confirmed that, a section of the Western immunoblot presented in Figure 3 (beta-Actin) overlaps, apart from a minor modification, with a section presented in a figure (Figure 4) in an earlier publication [2] from a different authorship group. While the authors cooperated with the Editorial Office during the investigation, they were unable to satisfactorily explain the presence of this overlap. As a result, the Editorial Board and Editor-in-Chief were unable to confirm the reliability of the findings and subsequently decided to retract this paper as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30, accessed on 15 April 2024) and in line with the Committee on Publication Ethics retraction guidelines (https://publicationethics.org/retraction-guidelines, accessed on 15 April 2024).
This retraction was approved by the Editor-in-Chief of the journal Pharmaceuticals.
The authors disagree with this retraction.

References

  1. Huang, J.-Y.; Lin, Y.-C.; Chen, H.-M.; Lin, J.-T.; Kao, S.-H. RETRACTED: Adenine Combined with Cisplatin Promotes Anticancer Activity against Hepatocellular Cancer Cells through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795. [Google Scholar] [CrossRef]
  2. Su, W.-W.; Huang, J.-Y.; Chen, H.-M.; Lin, J.-T.; Kao, S.-H. Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade. Int. J. Med. Sci. 2020, 17, 678–684. [Google Scholar] [CrossRef] [PubMed]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Huang, J.-Y.; Lin, Y.-C.; Chen, H.-M.; Lin, J.-T.; Kao, S.-H. RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795. Pharmaceuticals 2025, 18, 263. https://doi.org/10.3390/ph18020263

AMA Style

Huang J-Y, Lin Y-C, Chen H-M, Lin J-T, Kao S-H. RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795. Pharmaceuticals. 2025; 18(2):263. https://doi.org/10.3390/ph18020263

Chicago/Turabian Style

Huang, Jhen-Yu, You-Cian Lin, Han-Min Chen, Jiun-Tsai Lin, and Shao-Hsuan Kao. 2025. "RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795" Pharmaceuticals 18, no. 2: 263. https://doi.org/10.3390/ph18020263

APA Style

Huang, J.-Y., Lin, Y.-C., Chen, H.-M., Lin, J.-T., & Kao, S.-H. (2025). RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795. Pharmaceuticals, 18(2), 263. https://doi.org/10.3390/ph18020263

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop