Next Article in Journal
CDK11 Loss Induces Cell Cycle Dysfunction and Death of BRAF and NRAS Melanoma Cells
Previous Article in Journal
Role of TRPV1 and TRPA1 Ion Channels in Inflammatory Bowel Diseases: Potential Therapeutic Targets?
Previous Article in Special Issue
Curcumin and (−)- Epigallocatechin-3-Gallate Protect Murine MIN6 Pancreatic Beta-Cells against Iron Toxicity and Erastin-Induced Ferroptosis
Article Menu

Export Article

Open AccessArticle
Pharmaceuticals 2019, 12(2), 49; https://doi.org/10.3390/ph12020049

Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil

1
Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
2
Australian Research Council Centre of Excellence in Plant Energy Biology, School of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, PMB 1, Glen Osmond, SA 5064, Australia
3
Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
4
Department of Pathology, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
5
Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, UPM Serdang 43400, Selangor DE, Malaysia
6
Young Researchers and Elite Club, Islamic Azad University, Kermanshah, Iran
*
Author to whom correspondence should be addressed.
Received: 27 February 2019 / Revised: 19 March 2019 / Accepted: 26 March 2019 / Published: 1 April 2019
(This article belongs to the Special Issue Plant Phytochemicals on Drug Development)
  |  
PDF [286 KB, uploaded 1 April 2019]
  |  

Abstract

Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic. The constituents of essential oils isolated by hydro-distillation were examined by GC-MS and a total of 18 components were identified. The essential oil was dominated by oxygenated sesquiterpenes (44.4%), sesquiterpene hydrocarbons (33.3%), and oxygenated monoterpenes (16.6%). Caryophyllene (37.45%), germacrene D (16.17%), and humulene (13.66%) were the major components. The essential oils from A. vulgaris showed bactericidal and fungicidal properties against Staphylococcus aureus and Candida albicans, respectively. Anthelmintic activity against Haemonchus contortus was absent in this essential oil. Altogether above results indicate that essential oils from A. vulgaris can be used for various medicinal purposes. View Full-Text
Keywords: anthelmintic; antimicrobial; (compositae); caryophyllene; germacrene-D; humulene; GCMS-chromatography anthelmintic; antimicrobial; (compositae); caryophyllene; germacrene-D; humulene; GCMS-chromatography
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Malik, S.; de Mesquita, L.S.S.; Silva, C.R.; de Mesquita, J.W.C.; de Sá Rocha, E.; Bose, J.; Abiri, R.; de Maria Silva Figueiredo, P.; Costa-Júnior, L.M. Chemical Profile and Biological Activities of Essential Oil from Artemisia vulgaris L. Cultivated in Brazil. Pharmaceuticals 2019, 12, 49.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Pharmaceuticals EISSN 1424-8247 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top