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Pharmaceuticals 2017, 10(1), 14;

Aptamers in Bordeaux, 24–25 June 2016

ARNA Laboratory, Inserm U1212, CNRS UMR5320, University of Bordeaux, Bordeaux 33076, France
Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
Unit Chemical Biology and Medicinal Chemistry, University of Bonn, Bonn 53121, Germany
Department of Biology, Technical University Darmstadt, Darmstadt 64287, Germany
CEA, DRF, I2BM, MIRCen, CNRS UMR 9199, University Paris Saclay, Fontenay aux Roses 92265, France
Department of Surgery, Duke University, Durham, NC 27710, USA
Institute of Experimental Endocrinology and Oncology, CNR, Naples 80145, Italy
Department of Molecular Pharmacochemistry, CNRS UMR5063, University Grenoble Alpes, Saint Martin d’Hères 38400, France
Author to whom correspondence should be addressed.
Academic Editors: Alfredo Berzal-Herranz and Cristina Romero-López
Received: 16 November 2016 / Revised: 12 January 2017 / Accepted: 13 January 2017 / Published: 20 January 2017
(This article belongs to the Special Issue Aptamers: Biomedical Interest and Applications)
Full-Text   |   PDF [193 KB, uploaded 20 January 2017]


The symposium covered the many different aspects of the selection and the characterization of aptamers as well as their application in analytical, diagnostic and therapeutic areas. Natural and artificial riboswitches were discussed. Recent advances for the design of mutated polymerases and of chemically modified nucleic acid bases that provide aptamers with new properties were presented. The power of aptamer platforms for multiplex analysis of biomarkers of major human diseases was described. The potential of aptamers for the treatment of cancer or cardiovascular diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. A second edition of “Aptamers in Bordeaux” will take place on September 2017 ( View Full-Text
Keywords: aptamer; in vitro selection; SELEX; riboswitch; oligonucleotide; biosensor; cardiovascular; cancer; cell-targeted aptamers; imaging; synthetic biology aptamer; in vitro selection; SELEX; riboswitch; oligonucleotide; biosensor; cardiovascular; cancer; cell-targeted aptamers; imaging; synthetic biology
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Toulmé, J.-J.; Giangrande, P.H.; Mayer, G.; Suess, B.; Ducongé, F.; Sullenger, B.; de Franciscis, V.; Darfeuille, F.; Peyrin, E. Aptamers in Bordeaux, 24–25 June 2016. Pharmaceuticals 2017, 10, 14.

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