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Article

Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems

by
Norjihan Abdul Ghani
1,2,*,
Bintang Annisa Bagustari
1,
Muneer Ahmad
3,*,
Herman Tolle
2 and
Diva Kurnianingtyas
2
1
Department of Information Systems, Faculty of Computer Science and Information Technology, Universiti Malaya, Kuala Lumpur 50603, Malaysia
2
Fakultas Ilmu Komputer, Universitas Brawijaya, Jl. Veteran No. 10-11, Malang 65145, Jawa Timur, Indonesia
3
Department of Computer Science, University of Roehampton, London SW15 5PH, UK
*
Authors to whom correspondence should be addressed.
Sensors 2025, 25(24), 7583; https://doi.org/10.3390/s25247583 (registering DOI)
Submission received: 21 October 2025 / Revised: 25 November 2025 / Accepted: 4 December 2025 / Published: 14 December 2025
(This article belongs to the Special Issue Edge Artificial Intelligence and Data Science for IoT-Enabled Systems)

Abstract

The integration of the Internet of Things (IoT) and edge computing is transforming healthcare by enabling real-time acquisition, processing, and exchange of sensitive patient data close to the data source. However, the distributed nature of IoT-enabled smart healthcare systems exposes them to severe security and privacy risks during health information exchange (HIE). This study proposes an edge-enabled hybrid encryption framework that combines elliptic curve cryptography (ECC), HMAC-SHA256, and the Advanced Encryption Standard (AES) to ensure data confidentiality, integrity, and efficient computation in healthcare communication networks. The proposed model minimizes latency and reduces cloud dependency by executing encryption and verification at the network edge. It provides the first systematic comparison of hybrid encryption configurations for edge-based HIE, evaluating CPU usage, memory consumption, and scalability across varying data volumes. Experimental results demonstrate that the ECC + HMAC-SHA256 + AES configuration achieves high encryption efficiency and strong resistance to attacks while maintaining lightweight processing suitable for edge devices. This approach provides a scalable and secure solution for protecting sensitive health data in next-generation IoT-enabled smart healthcare systems.
Keywords: IoT-based smart healthcare; edge-enabled encryption; health information exchange; hybrid algorithms IoT-based smart healthcare; edge-enabled encryption; health information exchange; hybrid algorithms

Share and Cite

MDPI and ACS Style

Ghani, N.A.; Bagustari, B.A.; Ahmad, M.; Tolle, H.; Kurnianingtyas, D. Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems. Sensors 2025, 25, 7583. https://doi.org/10.3390/s25247583

AMA Style

Ghani NA, Bagustari BA, Ahmad M, Tolle H, Kurnianingtyas D. Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems. Sensors. 2025; 25(24):7583. https://doi.org/10.3390/s25247583

Chicago/Turabian Style

Ghani, Norjihan Abdul, Bintang Annisa Bagustari, Muneer Ahmad, Herman Tolle, and Diva Kurnianingtyas. 2025. "Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems" Sensors 25, no. 24: 7583. https://doi.org/10.3390/s25247583

APA Style

Ghani, N. A., Bagustari, B. A., Ahmad, M., Tolle, H., & Kurnianingtyas, D. (2025). Edge-Enabled Hybrid Encryption Framework for Secure Health Information Exchange in IoT-Based Smart Healthcare Systems. Sensors, 25(24), 7583. https://doi.org/10.3390/s25247583

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